Hydroxyethyl starch or gelatin, which is safer for the kidneys?

Dewi Wara Shinta and Junaidi Khotib and Mahardian Rahmadi and Budi Suprapti and E Rahardjo and JK. Wijoyo (2017) Hydroxyethyl starch or gelatin, which is safer for the kidneys? In: Unity in Diversity and the Standardisation of Clinical Pharmacy Services. Taylor adn Francis, London, pp. 281-286. ISBN 978-1-138-08172-7

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The aim of this study was to compare the effects of TIES 200/0.5 and gelatin in the kidneys with a dose of < 20 ml/kg/day. This is an observational study conducted in patients who underwent elective surgery al Dr. Soetomo Hospital with the bleeding condition being 1$^ 30% of EBV (Estimated Blood Volume) and a resuscitation fluid of HES 200/0.5 or modified fluid gelatin. The observed parameters were the ratio of NAG/urinary creatinine and serum creatinine. The results indicated that there was a significant increase in the NAG/crcatinine ratio in the HES 200/0.5 group (p = 0.0004 ), with no significant increase in modified gelatin. By contrast, the gelatin group showed a significant increase in serum creatinine (p < 0.000!) compared with the HES group. However, the increase in the NAG/urinary creatinine ratio and scrum creatinine in both groups was within the normal limits. HES 200/0.5 or modified gelatin at a dose of < 20 ml/kg/day in surgery patients does not lead to changes in kidney function.

Item Type: Book Section
Uncontrolled Keywords: gelatin
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi
Dewi Wara ShintaNIDN0018108502
Junaidi KhotibNIDN0022107001
Mahardian RahmadiNIDN0014038102
Budi SupraptiNIDN0014116104
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 21 Dec 2020 07:23
Last Modified: 21 Dec 2020 07:23
URI: http://repository.unair.ac.id/id/eprint/101181
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