Retno Indrawati, - and Muhammad Luthfi, - and Aqsa Sjuhada Oki, - and Yuliati, - and Agung Sosiawan, - and Priyawan Rachmadi, - and Muhaimin Rifai, - (2020) Analysis of Interleukin-10 Anti-inflammatory Cytokines in Salivary Lymphocyte Surface: A cross Sectional Study. Journal of International Oral Health, 12 (5). pp. 439-442. ISSN 09767428, 097 61799

	Text (ARTICLE) Analysis of Interleukin-10 Anti-inflammatory Cytokines in.pdf Download (374kB)
	Text (SIMILARITY) Analysis of Interleukin-10 Anti-inflammatory Cytokines in Salivary Lymphocyte Surface A cross sectional study.pdf Download (1MB)
	Text (PEER REVIEW) Analysis of Interleukin-10.pdf Download (423kB)
	Text (VALIDASI) 10.Dr.Lutfi(Analysis of Interleukin-10...pdf Download (978kB)
	Text (VALIDASI2) c-16.pdf Download (3MB)
	Text (PENILAIAN) 16. PENILAIAN KARIL DAN BIDANG ILMU.pdf Download (253kB)
	Text (PENILAIAN 2) 10. Kualitas Karil dan Kesesuaian Bidang Ilmu.pdf Download (683kB)
	Text (KORESPONDEN) 9. ANALYSIS OF IL-10 ANTI-INFLAMMATORY CYTOKINES EXPRESSION IN SALIVA OF SEVERE EARLY CHILDHOOD CARIE.pdf Download (1MB)
	Text (BUKTI KORESPONDEN) Koresponden.pdf Download (17MB)

Abstract

Aim: To analyze the expression of interleukin-10 (IL-10) in children with severe early childhood caries (S-ECC) and caries-free children. Materials and Methods: This was an observational analytic pilot study performed on children with social factors-ECC (S-ECC), and caries-free children as the objects of research with a cross-sectional study design. Saliva of children aged 4–6 years from the group of caries children in severe and caries-free early childhood was taken. Samples were taken by rinsing with 1.5% sterile NaCl for 30 s and then accommodated in a sterile tube, to get a 40 mL sample from the aforementioned procedure repeated four times. Flow-cytometry test was used to analyze the IL-10 expression. The results of the study were analyzed using the normality test using Shapiro–Wilk, then continued with t test using the Statistical Package for the Social Sciences (SPSS) software program,version 20.0 (IBM Corp., Armonk, NY, USA). The data were analyzed by independent t test to see the difference between cariesfree children and S-ECC. Results: The expression of IL-10 in the saliva of children with severe ECC was 3.32 ± 0.79; meanwhile, in caries-free children it was 4.04 ± 0.65. Conclusion: The IL-10 expression in children with severe ECC was ignificantly lower than that of in caries-free children

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