Agung Sosiawan, - and Mala Kurniati, - and Coen Pramono Danudiningrat, - and Indra Mulyawan, - and Abdul Hadi Furqoni, - and Indah Nuraini, - and Qurrota A’yun, - (2021) The Role of Cell-Free Fetal DNA as A Preventative Attempt to Decrease the Severity of Genetic Disorders: A Review. Medico-Legal Update, 21 (2). pp. 18-21. ISSN 0971720X

	Text (ARTICLE) The Role of Cell-Free Fetal DNA as A Preventative.pdf Download (380kB)
	Text (SIMILARITY) The Role of Cell-Free Fetal DNA as a Preventative Attempt to Decrease the Severity of Genetic Disorders_ A Review.pdf Download (1MB)
	Text (PEER REVIEW) the role of cell.pdf Download (365kB)
	Text (TURNITIN) 6. The Role of Cell-Free Fetal DNA as a Preventative Attempt to Decrease the Severity of Genetic Disorders_ A Review.pdf Download (1MB)
	Text (VALIDASI 2) 20. The Role of Cell-Free Fetal DNA as A Preventative Attempt to Decrease the Severity of Genetic Disorders A Review.pdf Download (2MB)
	Text (PENILAIAN) 6. PENILAIAN KARIL DAN BIDANG ILMU.pdf Download (277kB)

Abstract

The development of prenatal diagnosis has developed very rapidly over decades. Prenatal screening is applied to a mother with high-risk pregnancy (threatening the life of the fetus), such as a too-old mother or a too-young mother and having a certain disease in her medical history. Up until now, the curative method to treat genetic disorder is still developed and perfected. Therefore, a preventative action during pregnancy is important to do, such as Noninvasive Prenatal Testing (NIPT). NIPT method that is widely developed is the circulating cell-free fetal DNA (cffDNA) testing that can be useful for determining the fetal gender,the Identification of specific single-gene disorders, blood type, paternity determination, and the potency of regular use for testing chromosomal abnormalities. The detection of cell-free fetal DNA in the maternal blood circulation provides a new expectation for NIPT, especially preventing the severity of genetic disorders.

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