Brahmana Askandar, - and Nila Krisna Sari, - and Indra Yuliati, - and Lies Mardiyana, - (2020) Characteristics of Suspected Malignant Ovarian Tumor Patients Who Performed Surgery at Tertiary Referral Hospital. Systematic Review Pharmacy, 11 (5). pp. 181-184. ISSN 09762779

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Abstract

Ovarian cancer is often called as the silent killer because the symptoms appear when the stage is advanced. This study aimed to compare the identification of malignant ovarian tumor by RMI examination and abdominal pelvic CT scan to pathology examination as gold standard. This was a cross-sectional study. The data were obtained through medical records of a suspected malignant ovarian tumor patients who performed surgery at Dr. Soetomo General Hospital, Surabaya from January 2017 to December 2018. Among 64 patients, there were 56% of patients aged 41-60 years, 53% had a normal BMI, 56% multipara, and 56% not yet menopause. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of CA-125 diagnostic test were 80.85%, 17.65%, 73.1%, and 25%, respectively. RMI examination had a sensitivity of 82.98% and a specificity of 41.18%. Whereas, abdominal CT scan had a sensitivity of 87.23% and a specificity of 47.1%. Examination of RMI combined with abdominal pelvic CT scan had a sensitivity and specificity of 100% and 40%, respectively. RMI examination combined with abdominal pelvic CT scan gave better results in diagnosing ovarian malignancies.

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