Deny Saputra and Eha Renwi Astuti and Theresia Indah Budhy S. (2012) Apoptosis dan nekrosis sel mukosa rongga mulut akibat radiasi sinar-x dental radiografik konvensional. Dentomaxxilofacial Radiology Dental Journal, 3 (1). pp. 36-40. ISSN 2087-1864

	Text (NASKAH) Artikel 38. Apoptosis dan nekrosis sel mukosa rongga mulut akibat radiasi sinar-x dental radiografik konvensional.pdf Download (477kB)
	Text (SIMILARITY) 38_Turnitin Apoptosis dan nekrosis sel mukosa rongga mulut akibat radiasi sinar-x.pdf Download (1MB)
	Text (VALIDASI) 38. Apoptosis dan nekrosis sel mukosa rongga mulut akibat radiasi sinar-x dental radiografik konvensional.pdf Download (465kB)

Abstract

Background : Despite wide use as a diagnostic tool in medical and dental practice, conventional dental x-ray radiography is a common source of low-dose diagnostic radiation exposure wich may induce DNA damage and the result of cell death (apoptotic and necrotic cells). Purpose : The objective of this study was to examine the effect of conventional dental x-ray radiation on expression of apoptotic and necrotic in oral mucosa cell male rats (rattus norvegicus var. wistar). For this study on experimental laboratories technique was done. Method. Twenty four male wistar rats (150 g) were radiated with 0 mSv, 0,08 mSv, 0,16 mSv, 0,24 mSv of dental x-rays, with the mouth to the source. Oral mucosa cells was collected ten days after radiation were analysed for apopotic cells using immunohistochemistry (Apo-BrdU-IHCTM) and necrotic cells using histology (Hematoxillin Eosin). Apoptotic and necrotic cells examined under light microscope at 1000x magnification. Result. Using test of one way anova showed that conventional dental x-ray radiation to mouth of rat can cause significant differences expression of apoptotic and necrotic on oral mucosa cells. Using correlation test showed a significant influences of positive correlation. Conclusion : Apoptotic and necrotic cell was increase associated with higher dose of conventional dental x-ray radiation in oral mucosa cells

Actions (login required)

View Item