PEMBERIAN EKSTRAK AIR TERIPANG EMAS (Stichopus hermanii) TERHADAP PENINGKATAN JUMLAH LIMFOSIT PADA PENYEMBUHAN ULKUS TRAUMATIKUS MUKOSA RONGGA MULUT TIKUS WISTAR

DANIA MAHARANI, 021111037 (2014) PEMBERIAN EKSTRAK AIR TERIPANG EMAS (Stichopus hermanii) TERHADAP PENINGKATAN JUMLAH LIMFOSIT PADA PENYEMBUHAN ULKUS TRAUMATIKUS MUKOSA RONGGA MULUT TIKUS WISTAR. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Background: Indonesia is a country with the world’s biggest potential and producer of sea cucumbers. Golden sea cucumber contains glicosaminaglycans such as heparin sulphate and chondroitin sulphate, that could have a positive implication on wound healing process. This acceleration of wound healing could be observed with the increase in the number of lymphocytes in healing process of ulcus traumaticus. Methods: Golden sea cucumber extraxt was made with freeze-dried method, then prepared gel based using PEG 400 and PEG 4000 solvent. The experimental animals, in which have been made mucosal ulcus, were divided into a control group and a treatment group to be applied into golden sea cucumber extract with concentration of 20%, 40% and 80%. All sample were euthanized on day 4 and then made a preparation histopathology to count the number of lymphocytes. Results: One way annova test showed a significant difference between the control and treatment group. Tukey HSD showed a significant difference between control group and 40% concentration golden sea cucumber application. Conclusion: The addition of golden sea cucumber (Stichopus hermanii) extract is proven in increasing the number of lymphocytes with an optimal concentration of 40% at traumatic ulcer in Wistar rat’s oral mucous.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK KG. 88/15 Mah p
Uncontrolled Keywords: WOUND HEALING; STICHOPUS HERMANII'S EXTRACT; LYMPHOCYTES
Subjects: R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi
Creators:
CreatorsNIM/NIDN
DANIA MAHARANI, 021111037UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorIra Arundina, Dr., drg.,M.SiUNSPECIFIED
Depositing User: S.Sos. Sukma Kartikasari
Date Deposited: 28 Jan 2015 12:00
Last Modified: 26 Jul 2016 02:37
URI: http://repository.unair.ac.id/id/eprint/19436
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