PERAN FLAVONOID DAN CAPE DALAM PROPOLIS TERHADAP INDUKSI FmROPLASIA DAN EPITELISASI PADA PENYEMBUHAN LUKA PASCA EKSTRAKSI GIGI (Penelitian Eksperimenta1 Laboratoris)

RAHMA AULIA LESTARI, 020911093 (2013) PERAN FLAVONOID DAN CAPE DALAM PROPOLIS TERHADAP INDUKSI FmROPLASIA DAN EPITELISASI PADA PENYEMBUHAN LUKA PASCA EKSTRAKSI GIGI (Penelitian Eksperimenta1 Laboratoris). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Tooth extraction is the most common treatment ill dentistl~y. There are mOlIV complications in post extraction wound. One of the preventive Ireatment is llsing topical agents such as propolis. Propolis is a bee product that used os wound healing therapv. Propolis contains flavonoids and CAPE that can enhance fibropll/sia and epithelializatio/l in post-extraxction wound. Purposes: The aims of this stud.v well' sfud.ving .fibroplasia and epithelization during post extraction wound healing using .tiav(lnoids and CAPE in rats. Methods: This research used 32 Whistar rats divided into 2 groups, control group (K) and treated group (P), each group was divided into 2 sub-groups hased on time of samples coUeting. Central lejt incisors on each group extracted then pos/ ('.·traction V!)()und in group P was treated by 10% propolis gel-with active ingredientflavonoid and CAPE v-,'hile in grollp K was treated by 100% gel. The rats were sacrified at 3'd and days (lfler extructioll. The fibroplasia and epithelizations are showed by counted amount ,}ffibroblas and epithelial layers from HPA preparations mandibular biopsy results. Result..·: ]0% propolis gel I1Uh active ingredients flavonoid and CAPE couldn 'f increase amow/I offibrobl£lst signilicalllir (p>O.05). But, it could increase amount of epi/iJelial layers (p<()J)5). Conclusion: f(J(:~) propolis gel with active ingredients .flavonoid and CAPE could illcrease proliferation phose oj'post extraction wound healing, especially on collagen maturatj,m andfibrocytefbrma/ioJ7. But, it has no significant effect on fibroblas formation. Epitheliolization increase is I1Wr/il'd by increas amount ofepithelial layers and epithelial vl'ound cl(Jc)'ur,

Item Type: Thesis (Skripsi)
Additional Information: KKA KK KG 143/13 Les p
Uncontrolled Keywords: FLAVONOID
Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions: 02. Fakultas Kedokteran Gigi
Creators:
CreatorsEmail
RAHMA AULIA LESTARI, 020911093UNSPECIFIED
Depositing User: Mrs. Djuwarnik Djuwey
Date Deposited: 02 Jan 2014 12:00
Last Modified: 08 Sep 2016 01:37
URI: http://repository.unair.ac.id/id/eprint/19471
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