STUDI PENGGUNAAN ANTIKOAGULAN PADA PASIEN INFARK MIOKARD AKUT: Di Instalasi Rawat Inap Jantung RSUD Dr. Soetomo Surabaya

SALEAN, EKA YEHEZKIE CHRISTIANANTA (2015) STUDI PENGGUNAAN ANTIKOAGULAN PADA PASIEN INFARK MIOKARD AKUT: Di Instalasi Rawat Inap Jantung RSUD Dr. Soetomo Surabaya. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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FF FK 08-15 Sal s - adln.pdf

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12. BAB I PENDAHULUAN.pdf
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Official URL: http://lib.unair.ac.id

Abstract

Acute myocardial infarction is the demise or necrosis of myocardial due to the decreased amount of oxygen and blood supply to myocardial. This ischemia is mostly triggered by erosion or rupture of the atherosclerotic plaque. Consequently, it forms thrombus, which causes constriction in artery. The therapy for myocardial infarction is mainly purposed to support the coronary artery blood flow. Furthermore, anticoagulant is one of the antithrombotic agents in acute myocardial infarction therapy. The aims of this study are to know anticoagulants usage towards patients with acute myocardial infarction and identify whether there is any drug related problems (DRPs) of it. This is a retrospective study of 1 January – 31 December 2014 period at Department of Cardiology Inpatient Care Dr. Soetomo Hospital Surabaya. The obtained data were compared with the available guidelines, journals, and textbooks. The result of the study involving 34 patients with acute myocardial patients revealed that most patients were male, aged 60-74 (68%). The most anticoagulants used were enoxaparin (88%) at dose 1 x 60mg, 2 x 40mg, and 2 x 60mg, and fondaparinux (12%) at dose 1 x 2,5mg with subcutaneous abdomen route. DRPs that are found in this study were adverse drug reaction of enoxaparin such as hemorrhage, which is indicated by hematuria and thrombocytopenia. To conclude, drug utilization of anticoagulants towards patients with acute myocardial infarction at Dr. Soetomo Hospital Surabaya was appropriate according to the guidelines of acute myocardial infarction

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF FK.08/15 Sal s
Uncontrolled Keywords: Anticoagulants; acute Myocardial Infarction; Drug Utilization Study
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmasi Klinis
Creators:
CreatorsNIM/NIDN
SALEAN, EKA YEHEZKIE CHRISTIANANTAUNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorHasmono, DidikUNSPECIFIED
Depositing User: sugiati
Date Deposited: 30 Mar 2016 06:59
Last Modified: 31 Mar 2016 01:24
URI: http://repository.unair.ac.id/id/eprint/19917
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