Noke Aresanty, 020513504 (2008) PENURUNAN JUMLAH DAN MACAM KOLONI BAKTERI RONGGA MULUT DALAM SALIVA AKIBAT PENGGUNAAN OBAT KUMUR YANG MENGANDUNG ASAM HIALURONIK 0,1% DAN 0,025%. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Background. Oral cavity has the greatest number of bacteria variations in our body. Oral cavity also connnected our vital system such as respirator ian system and gastrointestinal system. So it is very important to maintain our mouth’s health. Th ere are many ways to keep our mouth’s health, one of them is using mouthwash. Many people like use mouthwash because some of it’s benefit, such as it’s prac ticality, easy to get, and achievable. One of mouthwash kind is contai n hyaluronic acid. Some of hyaluronic acid purpose is to inhibit bacteria ’s growth, stimulate tissue regeneration, and accelerate healing of gingivitis. There are many variati on of hyaluronic acid consentration in the market. Inappropiate use have harmful consequences for user. Purpose. The aim of this study was to ascertain the lo west concentration is good e nough in reduction number and types bacteria colony wich appropiate with antibiotic medicinal tretment principal. Method. This research was done in experiment al laboratories form thrity healthy subjects. All the volunteers were divided in to three groups: 10 su bjects per group. Subjects’ saliva was collected early in the morning after nor mal oral hygienic procedures. The saliva samples collected in the first day for each group served as the control and the samples collected after 1 weeks of da ily use of the grouped mouth rinse. Results. There were significant differences of bacterial’s co lony number and types reduction as the result of mouthwash use containing hyaluroni c acid 0,1 % and 0,025 % (p<0.05). Conclusion. Use of mouthwash containi ng hyaluronic acid 0,025% is good enough to decrease bacteria colony number and types. Keywords. Hyaluronic acid, oral cav ity bacteria, mouthwash.

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