Benda Alifianti Suwito (2015) The Effect Of Endosulfan On Histopathological Changes Of Mus Musculus Lung. Skripsi thesis, UNIVERSITAS AIRLANGGA.

	Text (COVER) 1. COVER.pdf Download (54kB)
	Text (ABSTRACT) 2. ABSTRACT.pdf Download (33kB)
	Text (TABLE OF CONTENT) 3. TABLE OF CONTENTS.pdf Download (50kB)
	Text (CHAPTER 1) 4. CHAPTER 1 INTRODUCTION.pdf Download (50kB)
	Text (CHAPTER 2) 5. CHAPTER 2 LITERATURE REVIEW.pdf Restricted to Registered users only until 28 May 2023. Download (133kB) | Request a copy
	Text (CHAPTER 3) 6. CHAPTER 3 MATERIALS AND METHODS.pdf Restricted to Registered users only until 28 May 2023. Download (53kB) | Request a copy
	Text (CHAPTER 4) 7. CHAPTER 4 RESEARCH RESULTS.pdf Restricted to Registered users only until 28 May 2023. Download (326kB) | Request a copy
	Text (CHAPTER 5) 8. CHAPTER 5 DISCUSSION.pdf Restricted to Registered users only until 28 May 2023. Download (54kB) | Request a copy
	Text (CHAPTER 6) 9. CHAPTER 6 CONCLUSION AND SUGGESTIONS.pdf Restricted to Registered users only until 28 May 2023. Download (39kB) | Request a copy
	Text (REFERENCES) 10. REFERENCES.pdf Restricted to Registered users only until 28 May 2023. Download (60kB) | Request a copy
	Text (APPENDIX) 11. APPENDIX.pdf Restricted to Registered users only until 28 May 2023. Download (255kB) | Request a copy

Abstract

The aim of this research was to know histopathological changes of lung mice (Mus musculus) caused by Endosulfan. Twenty male mice with 20 gram bodyweight, were adapted for seven days and divided into four groups. Per-oral exposure using single dose of endosulfan for each treatment. On day eight each group (P0, P1, P2, P3) were treated with no endosulfan, 6.25mg, 12.5mg and P3 25mg/KgBW/1ml/oral of endosulfan. On the tenth day, necropsy was done by collecting the lung and did histopathology slide. The research design was Post Test Only Control Group Design. Data was analyzed using Kruskal-Wallis test, the result showed there were significant difference (P<0,05) and was continued with Mann-Whitney test. The result showed that endosulfan caused histopathological changes of lung mice such as congestion, hemorrhage, emphysema, and inflammation. The highest dose 25mg/KgBW can cause the highest lung damage and even death. The medium dose can cause average lung damage. The lowest dose 6,25mg/KgBB can cause the lowest lung damage.

Item Type:	Thesis (Skripsi)
Additional Information:	KKC KK KH.164/15 Suw e
Uncontrolled Keywords:	ENDOSULFAN
Subjects:	Q Science
Divisions:	06. Fakultas Kedokteran Hewan
Creators:	Creators NIM Benda Alifianti Suwito NIM061111008
Contributors:	Contribution Name NIDN / NIDK Thesis advisor Rudy Sukamto Setiabudi UNSPECIFIED Thesis advisor Hani Plumeriastuti NIDN0008085905
Depositing User:	Ms noviyanti wulandari
Date Deposited:	13 Jan 2016 12:00
Last Modified:	28 May 2020 10:12
URI:	http://repository.unair.ac.id/id/eprint/20740
Sosial Share:

Actions (login required)

View Item