PENGARUH PEMBERIAN VITAMIN E (α-tocopherol) TERHADAP JUMLAH HITUNG SEL LEYDIG PADA MENCIT YANG DIPAPAR 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD)

NURIL LISARAMANIA, 061011003 (2014) PENGARUH PEMBERIAN VITAMIN E (α-tocopherol) TERHADAP JUMLAH HITUNG SEL LEYDIG PADA MENCIT YANG DIPAPAR 2,3,7,8-tetrachlorodibenzo-pdioxin (TCDD). Skripsi thesis, UNIVERSITAS AIRLANGGA.

[img]
Preview
Text (abstrak)
gdlhub-gdl-s1-2014-ramanianur-32035-4.abstr-t.pdf

Download (182kB) | Preview
[img] Text (fulltext)
fulltext.pdf
Restricted to Registered users only

Download (2MB) | Request a copy
Official URL: http://lib.unair.ac.id

Abstract

The goal of this research was to verify the effect of vitamin E (α-tocopherol) on the number of Leydig cell in mice treated with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Five experimental groups of a combination of TCDD and vitamin E were designed as follows: 0 ng/kg/d and 0 mg/kg/d (P0), 100 ng/kg/d and 0 mg/kg/d (P1), 100 ng/kg/d and 11 mg/kg/d (P2), 100 ng/kg/d and 20 mg/kg/d (P3), and 100 ng/kg/d and 37 mg/kg/d (P4) respectively. Vitamin E and TCDD were given by oral gavage for 9 days. The results demonstrated that 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) could have any effect on male germ cells especially Leydig cell. TCDD decreased the number of Leydig cell in intertitial seminiferous tubule. Vitamin E (α-tocopherol), which is knownly well to have potential as an antioxidant, to protect the demage to the body caused by exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Best dose of vitamin E is 37 mg/kg/d increased the number of Leydig cell as well as negative control.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH. 51/14 Ram p
Uncontrolled Keywords: VITAMIN E; LEYDIG CELLS
Subjects: Q Science > QL Zoology > QL1-991 Zoology
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsEmail
NURIL LISARAMANIA, 061011003UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorAjik Azmijah, S.U., drhUNSPECIFIED
Depositing User: Ani Sistarina
Date Deposited: 17 Jun 2014 12:00
Last Modified: 06 Sep 2016 02:40
URI: http://repository.unair.ac.id/id/eprint/21357
Sosial Share:

Actions (login required)

View Item View Item