Safda Farizy Ridho, 060710370 (2013) GAMBARAN HISTOPATOLOGI GINJAL TIKUS PUTIH JANTAN PADA KASUS PATAH TULANG FEMUR DENGAN TERAPI EKSTRAK TANAMAN Cissus quadrangularis DAN KALSIUM KARBONAT. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Cissus quadrangularis is a plant used often to treat fracture and very good for bone healing process. The aim of this study was conducted renal histopathology of male rats (Rattus norvegicus) after reposition of femoral fracture with terapy Cissus quadrangularis and Calcium carbonate. This study used 18 male rats (Rattus norvegicus). Age of 12 weeks after 1 week of adaptation, all rats wore treated reposition of femoral dexter fracture with intramedullary pin fixation. The rats model were evenly randomly divided into three groups at 2 weeks after survey. Groups I treated with normal diet, group II with normal diet + Cissus quadrangularis 500 mg/day per oral, and group III with normal diet + Calcium carbonate suplement 150 mg/day. At the end of the experiment all the rats were killed, subsequently renal were taken out for determine the histopathological examination. The histopathological examination used Kruskall Wallis test. The results of this study indicated there was noticeable difference between Cissus quadrangularis and Calcium carbonate. This study suggested the used of Cissus quadrangularis for fracture treatment was still better than Calcium carbonate.

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