PENGARUH PEMBERIAN EKSTRAK JINTAN HITAM (Nigella sativa) TERHADAP KADAR SGOT-SGPT PADA TIKUS PUTIH (Rattus novergicus) YANG MENDERITA DIABETES MELLITUS (DM) TIPE 1

DIKKY EKA MANDALA PUTRANTO, 060810015 (2013) PENGARUH PEMBERIAN EKSTRAK JINTAN HITAM (Nigella sativa) TERHADAP KADAR SGOT-SGPT PADA TIKUS PUTIH (Rattus novergicus) YANG MENDERITA DIABETES MELLITUS (DM) TIPE 1. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The aim of this study was to determine the effect of black cumin (Nigella sativa) extract on SGOT - SGPT in white rats (Rattus novergicus) with type 1 diabetes mellitus (DM). Twenty five, 2-3 month old male rats were randomly divided into five groups. Rats in negative control group were injected with physioligical saline while the others were injected with alloxan 150 mg/kg bw to induce type 1 diabetes mellitus. Rats in positive control group were not treated while alloxan induced diabetec rats were treated with black cumin (Nigella sativa) extract at the dose 5, 10, and 15 g/kg bw reopectively. Black cumin (Nigella sativa) extract was given orally for 14 days, then rats were anasthesia with cloroform to take blood sample examination. Data analysis using Analysis Of Variant (Anova / Anava) ; (α = 0,05) followed by BNJ test. The results of SGOT - SGPT examination of mice after treatment given extract of black cumin (Nigella sativa) dose of 5 g/kg bw, 10 g/kg bw, 15 g/kg bw, showed no significant effect on level of SGOT – SGPT.

Item Type: Thesis (Skripsi)
Additional Information: KKC. KK KH. 91/14 Put p
Uncontrolled Keywords: DIABETES MELLITUS
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM/NIDN
DIKKY EKA MANDALA PUTRANTO, 060810015UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorSoetji Prawesthirini, SU.,drhUNSPECIFIED
Depositing User: shiefti dyah alyusi
Date Deposited: 30 Jun 2014 12:00
Last Modified: 20 Sep 2016 05:17
URI: http://repository.unair.ac.id/id/eprint/21587
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