PENGARUH PAPARAN ENDOTOKSIN LIPOPOLISAKARIDA (LPS) DALAM DEBU KAYU TERHADAP PENINGKATAN KADAR INTERFERON GAMA (IFN-y) SERUM DAN PENURUNAN FAAL PARU PEKERJA DI PABRIK PENGOLAHAN KAYU SURABAYA

AWALUDDIN HIDAYAT RAMLI INAKU, 101314353001 (2015) PENGARUH PAPARAN ENDOTOKSIN LIPOPOLISAKARIDA (LPS) DALAM DEBU KAYU TERHADAP PENINGKATAN KADAR INTERFERON GAMA (IFN-y) SERUM DAN PENURUNAN FAAL PARU PEKERJA DI PABRIK PENGOLAHAN KAYU SURABAYA. Thesis thesis, UNIVERSITAS AIRLANGGA.

[img]
Preview
Text (ABSTRAK)
gdlhub-gdl-s2-2015-inakuawalu-39380-7.abstr-t.pdf

Download (568kB) | Preview
[img] Text (FULLTEXT)
1.pdf
Restricted to Registered users only

Download (3MB) | Request a copy
Official URL: http://lib.unair.ac.id

Abstract

Wood dust containing LPS (lipopolysaccharide) endotoxins can cause inflammation of the respiratory tract, decreased lung function, pneumonitis and affects serum levels of INF-#947;. The purpose of this study was to analyze the effect of endotoxin LPS to increased levels of IFN-#947; and decreased lung function of workers at the sawmill wood processing factories. Researchers study design using analytic observational prospective longitudinal study. The study sample consisted of 11 workers in the wood processing plant Margomulyo Surabaya. Techniques of data collection is done by conducting interviews, personal dust measurement, measurement of endotoxin private, workers took blood samples and perform spirometry tests. Blood serum taken aims to determine the level of IFN-#947; and lung function measured aims to determine the condition of the lungs of workers who are both measured at the time before and after work. IFN-#947; levels and lung function is the dependent variable. Meanwhile, private endotoxin levels as independent variables. Age, duration of work activity and smoking habits as a confounding variable. The findings of this study indicated that the average age of workers was 27.45 years old and most of them have worked for 5.73 years, and 64% of workers are light smokers. After working for 8 hours, found the average exposure of private wood powder 2.93 mg/m3 and average personal endotoxin levels was as much as 91.00 EU/m3. average of IFN-#947; in the blood serum of workers is 7.64 mg/l, or about 81.8% while the decline in FVC and FEV1, respectively 63.6% and 81.8%. Personal endotoxin levels did not have an effect on increasing blood serum IFN-#947; (multiple regression test, p>0.05), but have an effect on decreased lung function(multiple regression test, p<0.05).

Item Type: Thesis (Thesis)
Additional Information: KKC KK TKL 07-15 Ina p
Uncontrolled Keywords: sawdust, LPS endotoxin, lung function, interferon gamma (IFN-#947;), wood processing workers.s
Subjects: R Medicine > RC Internal medicine > RC705-779 Diseases of the respiratory system
T Technology > TS Manufactures > TS920-937 Chemical processing of wood
Divisions: 10. Fakultas Kesehatan Masyarakat > Magister Kesehatan Lingkungan
Creators:
CreatorsEmail
AWALUDDIN HIDAYAT RAMLI INAKU, 101314353001UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorUNSPECIFIEDUNSPECIFIED
Depositing User: Nn Sheli Erlangga Putri
Date Deposited: 2016
Last Modified: 19 Oct 2016 02:53
URI: http://repository.unair.ac.id/id/eprint/33744
Sosial Share:

Actions (login required)

View Item View Item