PENGARUH PAPARAN ENDOTOKSIN LPS DALAM DEBU PENGGILINGAN PADI TERHADAP PENINGKATAN KADAR C-REACTIVE PROTEIN (C-RP) SERUM DAN PENURUNAN FAAL PARU OPERATOR PENGGILINGAN PADI

FRIDA HENDRARINATA, 101314353004 (2015) PENGARUH PAPARAN ENDOTOKSIN LPS DALAM DEBU PENGGILINGAN PADI TERHADAP PENINGKATAN KADAR C-REACTIVE PROTEIN (C-RP) SERUM DAN PENURUNAN FAAL PARU OPERATOR PENGGILINGAN PADI. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

One of the agents which are contained in rice dust and become a trigger of inflammation at the respiratory canal is LPS endotoxin. The purpose of this study was analyzing the effect of the increase of LPS endotoxin toward the increase of C-RP serum and the decrease of LUNGS function of rice mill operator. This study was an analytical observational study by utilizing the design of longitudinal prospective study. The samples of this study were 11 operators of rice mill in Palur Kebonsari village, Madiun district. The techniques of data collection were interviewing, measuring the personal dust, measuring the personal LPS endotoxin, measuring the lungs function by utilizing spirometer and the content of C-RP before and after woring. The dependent variables of this study were the content of C-RP and lungs function. The independen mean variable of this study was the content of LPS endotoxin and Age, years of service served, and smoking habit as confounding variable.This study showed that the average of the was 5 years, the 63,6% of them were medium smokers. After working in 8 hours, it was obtained the content of personal dust that was 1,47 mg/mand the average of the content of LPS endotoxin was 91,1 EU/ m3. The increase of C-RP serum content of rice mill operator was 0,94 mg/L or about 45,5 %. The decrease mean of FVC and FEV1was 63,6% and 45,5%of each. Therefore, It is concluded that LPS endotoxin containing rice mill dust affected toward the increase of C-RP serum content and the decrease of lungs function (multiple regression test in p<0,05). Hence, it is be concluded that the increase of LPS endotoxin in rice dust affects the increase of C-RP serum content and decrease of pulmonary function.

Item Type: Thesis (Thesis)
Additional Information: KKC KK TKL 11-15 Hen p
Uncontrolled Keywords: grain dust, LPS endotoxin, pulmonary function, C-Reactive Protein (C-RP), the rice mill operator s
Subjects: R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine > RA565-600 Environmental health
Divisions: 10. Fakultas Kesehatan Masyarakat > Magister Kesehatan Lingkungan
Creators:
CreatorsNIM/NIDN
FRIDA HENDRARINATA, 101314353004UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorSOEDJAJADI KEMAN, prof.dr.M.S.PhDUNSPECIFIED
Depositing User: Nn Sheli Erlangga Putri
Date Deposited: 2016
Last Modified: 19 Oct 2016 02:41
URI: http://repository.unair.ac.id/id/eprint/33751
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