Pengaruh Pemberian Probiotik Mengandung Lactobacillus Reuteri terhadap Jumlah CD4+ dan Status Gizi Usia Lanjut (Studi di Panti Jompo Jaga Mara Pati Kabupaten Buleleng, Bali)

IDA AYU PUTU PERTIWI, 090810205 (2011) Pengaruh Pemberian Probiotik Mengandung Lactobacillus Reuteri terhadap Jumlah CD4+ dan Status Gizi Usia Lanjut (Studi di Panti Jompo Jaga Mara Pati Kabupaten Buleleng, Bali). Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The number of elderly is rapidly increase, including in Indonesia. With aging, comes a reduction in overall health and increased morbidity and mortality due to infectious disease. One of the major cause is the immunity changes with aging including inhibited Cell Mediated Immunity. One of the cells that has important role in Cell Mediated Immunity is CD4+. Giving probiotic containing L. reuteri is expected to stimulate immune function including increase the number of CD4+, which in turn can improve the nutritional status in elderly. The purpose of this study was to analyze the effect of probiotic containing L. reuteri on number of CD4+ and nutritional status in elderly. This study was randomized experimental study using Pre Test Post Test Control Group Design with a double blind treatment. The research population was all health elderly aged 60-80 years old at Panti Jompo Jaga Mara Pati Buleleng, Bali. The samples consist of two groups, treatment and control group, each of the samples in group was 13 elderly. The treatment group were given probiotic tablet each contain 6,5 billion L. reuteri for 4 weeks, while the control group given nothing. The result showed that after intervention, there were no differences in number of CD4+ between treatment group and control group with p = 0,290 ( = 0,05). To nutritional status, there were no differences between treatment group and control group with p = 0,317 ( = 0,05). But there are significant differences in morbidity due to infectious disease during supplementation between treatment group and control group with p = 0,030 ( = 0,05). From this research can be concluded that there are no differences in number of CD4+ and nutritional status between treatment group and control group. But there are differences in morbidity due to infectious disease between treatment group and control group. There for, further research needed to determine the effect of probiotic to infectious disease.

Item Type: Thesis (Thesis)
Additional Information: KKC KK TKM 39 / 11 Per p
Uncontrolled Keywords: L. reuteri, number of CD4+, nutritional status, elderly
Subjects: R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA421-790.95 Public health. Hygiene. Preventive medicine > RA773-788 Personal health and hygiene
T Technology > TX Home economics > TX341-641 Nutrition. Foods and food supply
Divisions: 10. Fakultas Kesehatan Masyarakat > Magister Ilmu Kesehatan Masyarakat
Creators:
CreatorsNIM/NIDN
IDA AYU PUTU PERTIWI, 090810205UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorBambang W., Prof., dr., MS., MCN., PhD., Sp.GKUNSPECIFIED
ContributorMerryana Adriani, Dr., S.KM., M.KesUNSPECIFIED
Depositing User: Nn Husnul Khotimah
Date Deposited: 2016
Last Modified: 09 Apr 2019 08:13
URI: http://repository.unair.ac.id/id/eprint/36386
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