ADHIYANTI ASIKIN, 100941038 (2011) PENGARUH ZINC SULPHAT TERHADAP PENINGKATAN JUMLAH LIMFOSIT T � CD4 PADA PASIEN HIV/AIDS DI UPIPI RSUD Dr SOETOMO SURABAYA. Thesis thesis, UNIVERSITAS AIRLANGGA.

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Abstract

HIV/AIDS impact on health, nutrition, food security and socio-economic development community and will affect the immune system of people living with HIV. People With HIV/AIDS requires a macronutrient-containing nutrients and micronutrients in sufficient quantities. Zinc supplementation is a way to provide additional zinc minerals from the foods we consume daily. Zinc is an essential component of the immune system and vital for the development of non-specific immunity and cell mediated immunity (especially CD4 cells). This study is a research Experimental research design Randomized Control Group Pretest Postest Design, with the provision of treatment in Double Blind. Goal of research is to analyze the effect of giving to the amount of zinc sulphat T lymphocytes - CD4 HIV/AIDS. The study population was all patients with HIV/ AIDS outpatient ICUID Dr. Soetomo Hospital Surabaya that has been getting ARVs. The sample in this study consisted of 26 patients with HIV/AIDS screening results are taken at random from the sub-populations and meet the inclusion criteria who received ARVs in the past year. Study sample consisted of two groups, namely the treatment and control groups. The results showed most of the samples in the treated group increased CD4 cell counts after the intervention were given zinc. Of paired-samples t test CD4 counts before and after intervention zinc showed no significant difference (p = 0.000). When viewed on the difference in the amount of increase of CD4 before and after treatment, t-2 test results free sample showed no significant difference increases the difference in CD4 cell counts in treatment group and control group (p = 1.000). This means that the average difference in CD4 cell counts in treatment groups were not significantly greater than the control group. Conclusion: There is a significant increase in the number of T lymphocytes - CD4 after intervention with zinc as compared with before the intervention sulphat zinc in patients with HIV/AIDS in ICUID Dr. Soetomo Hospital Surabaya

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