THE EFFECT OF L-ARGININE ON DECREASING FOAM CELL DEVELOPMENT AT POST SURGICAL EMBOLECTOMY WITH FOGARTY BALLOON CATHETER ON ILIAC ARTERIES OF RABBIT

FIRDAUSY KURNIA MAULANA, 061111087 (2015) THE EFFECT OF L-ARGININE ON DECREASING FOAM CELL DEVELOPMENT AT POST SURGICAL EMBOLECTOMY WITH FOGARTY BALLOON CATHETER ON ILIAC ARTERIES OF RABBIT. Skripsi thesis, Universitas Airlangga.

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Abstract

Vascular injury caused by Fogarty balloon catheter lead on endothelial dysfunction and trigger the development of foam cell, early atherosclerosis plaque. L-Arginine, as a nitric oxide precursor, has shown to decrease foam cell development. The aim of this study is to prove the effect of L-Arginine on the decreasing of amount of foam cell at post surgical embolectomy with Fogarty balloon catheter on iliac arteries of rabbit. Sixteen male rabbits were randomized divided into two group of treatment (n=8). After surgical embolectomy in right iliac artery has done, rabbits were fed standard ration (T0) and standard ration with oral L-Arginine (T1). At 28 days after surgical embolectomy, all samples were sacrificed for histopathological assesment. Based on unpaired t test result shows significantly different (p<0.05) between T0 (15.28 ± 13.60) and T1(3.96 ± 4.26). The conclusion of this research is L-Arginine affecting on the decreasing of amount of foam cell at post surgical embolectomy with Fogarty balloon catheter on iliac arteries of rabbit.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH 47-16 Mau e
Uncontrolled Keywords: Vascular injury, Fogarty balloon catheter, foam cells, L-Arginine, nitric oxide
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF911-914.4 Veterinary surgery
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsEmail
FIRDAUSY KURNIA MAULANA, 061111087UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorHj. Romziah Sidik, Prof. , drh., Ph. DUNSPECIFIED
ContributorNgakan Made Rai Widjaja, Dr. , drh., MSUNSPECIFIED
Depositing User: sukartini sukartini
Date Deposited: 27 Feb 2017 19:13
Last Modified: 27 Feb 2017 19:13
URI: http://repository.unair.ac.id/id/eprint/53656
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