UJI AKTIVITAS ANALGESIK EKSTRAK N-HEKSANA DAUN Marsilea crenata Presl. DENGAN METODE GELIAT PADA MENCIT

FATHIA FAZA RAHMADANITA, 051211132018 (2016) UJI AKTIVITAS ANALGESIK EKSTRAK N-HEKSANA DAUN Marsilea crenata Presl. DENGAN METODE GELIAT PADA MENCIT. Skripsi thesis, Universitas Airlangga.

[img]
Preview
Text (abstrak)
FF.FT. 14-16 Rah u abstrak.pdf

Download (206kB) | Preview
[img] Text (fulltext)
FF.FT. 14-16 Rah u.pdf
Restricted to Registered users only

Download (1MB) | Request a copy
Official URL: http://lib.unair.ac.id

Abstract

The objective of this study was to evaluate the analgesic activity of n-hexane extract of Marsilea crenata Presl. The analgesic effect was examined by acetic-acid-induced writhing response. Before intraperitoneally injection of acetic acid 0,6%, drugs were orally administered to Balb/C mice. This animal were divided into 5 groups, positive control (Ibuprofen 1,04 mg/20 g BW mice), negative control (10% tween 80), dose 1 (0,27 mg/20 g BW mice), dose 2 (0,54 mg/20 g BW mice), and dose 3 (0,81/20 g BW mice). The number of writhings exhibited by each animal was counted for thirty minute beginning five minute after acetic acid induction. Obtained data were analyzed by one-way ANOVA followed by LSD test with confident level 0,05. Dose 1, dose 2, and dose 3 showed significant different compare to negative control (p<0,05). Dose 1 (0,27 mg/20 g BW mice) almost equal to positive control (p>0,05). This study indicates that n-hexane extract of Marsilea crenata has analgesic effect. The obtained results provide information for the potential use in the treatment of pain. Keywords: Analgesic activity; N-heksana extract; Writhing method

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.FT. 14-16 Rah u
Uncontrolled Keywords: Analgesic activity; N-heksana extract; Writhing method
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM/NIDN
FATHIA FAZA RAHMADANITA, 051211132018UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorMangestuti Agil, Prof., MS.UNSPECIFIED
ContributorNeny Purwitasari, S.Farm, M.Sc.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 02 Apr 2017 17:22
Last Modified: 02 Apr 2017 17:22
URI: http://repository.unair.ac.id/id/eprint/55643
Sosial Share:

Actions (login required)

View Item View Item