PENGARUH GUGUS METOKSI TERHADAP PERSENTASE HASIL SINTESIS 2-METOKSI KHALKON, 2,4-DIMETOKSIKHALKON DAN 2,2’,4-TRIMETOKSIKHALKON

FENNY AGENG RIASTUTI, 051211131026 (2016) PENGARUH GUGUS METOKSI TERHADAP PERSENTASE HASIL SINTESIS 2-METOKSI KHALKON, 2,4-DIMETOKSIKHALKON DAN 2,2’,4-TRIMETOKSIKHALKON. Skripsi thesis, Universitas Airlangga.

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Official URL: http://lib.unair.ac.id

Abstract

THE INFLUENCE OF METHOXY GROUP TOWARD PERCENTAGE SYNTHESIS OF 2-METHOXY CHALCONE, 2,4-DIMETHOXYCHALCONE AND 2,2’,4-TRIMETHOXYCHALCONE Fenny Ageng R. The aim of this research was to determine the influence of methoxy group on synthesis chalcones derivative by comparing the yields of synthesis. A series of chalcones was prepared by Claisen - Schmidt condensation of appropriate acetophenones with appropriate benzaldehydes in the presence of sodium hydroxide and ethanol under microwave irradiation. The synthesis chalcones derivative was characterized by Uv Spectrophotometry, FT-IR, and H-NMR. The synthesis product of chalcones derivative is yellow crystal. The yield of chalcone is 75 % ± 2,35, the yield of 2-methoxychalcone is 85% ± 6,79, the yield of 2,4-dimethoxychalcone is 92% ± 0,47, and the yield of synthesis 2,2’,4;trimethoxychalcone is 95% ± 0,82. It can be conclude that methoxy group increase the yields of product. Keywords : chalcones, synthesis, microwave, methoxy group, NaOH, Claisen-Schmidt condensation.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF. KF. 18-16 Ria p
Uncontrolled Keywords: chalcones, synthesis, microwave, methoxy group, NaOH, Claisen-Schmidt condensation.
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Kimia Farmasi
Creators:
CreatorsEmail
FENNY AGENG RIASTUTI, 051211131026UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorTutuk Budiati, Prof. Dr. , Apt., MSUNSPECIFIED
ContributorSuzana, Dra., M.SiUNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 07 Apr 2017 01:42
Last Modified: 05 Sep 2017 21:53
URI: http://repository.unair.ac.id/id/eprint/56133
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