Uji aktivitas antimalaria ekstrak air daun johar (Cassia siamea Lamk) terhadap Plasmodium berghei secara in vivo

Achmad, Fuad Hafid and Ardhistia, Raharjo and Wiwied Ekasari, NIDN. 0022016902 (2014) Uji aktivitas antimalaria ekstrak air daun johar (Cassia siamea Lamk) terhadap Plasmodium berghei secara in vivo. Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 1 (1). pp. 6-9. ISSN 2406-9388

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Abstract

The water extract (f Ca;sia siamea l-arnk letf *,as evaluated for antj melaial actiil! in yiw, in 44ay snf,pressive assaJls against Plasmodiam beryhet in mice. An in vivo model lo exafiine the antimolarial tlfect cfplant extract is described. Selected mice (20-30 g bocly weight) were divi.ded into 6 groLps, each consist qf 6 mice. Each animal was it.jected with Plasmodium berghei irfected RBCs. Ihe assalt was done by Peter's test, mice werc trcated orally with diluted extract in dose leyels.f 12.5 mgkgbw,25 mgtkgbw,50 mg/kg bw, 100 mgtkg bw, 200 mgt*g bw for 5 groups. One grorp served as control The negative control was lreated with 0.502 CMC Na solution. The control posilive was treated &,ith a dose cf 10, 5, 1, 0.5,0.1, 0.05 ngtkg body u,eight Chloroquine diiphotphat solution. Ihe concentrqtion (f water exlract required Jbr 50?6 st4,pression lED5l cfPlasmodium berghei in nice was 83.77412 mgthg bw.

Item Type: Article
Uncontrolled Keywords: Cassia sianeq Lafirk, Pkxmodium berghei, Artimalarial activiry
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM/NIDN
Achmad, Fuad Hafidachmadfuad@ff.unair.ac.id
Ardhistia, RaharjoUNSPECIFIED
Wiwied Ekasari, NIDN. 0022016902wiwied-e@ff.unair.ac.id
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 08 May 2017 23:45
Last Modified: 10 Aug 2017 20:00
URI: http://repository.unair.ac.id/id/eprint/56623
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