Pengaruh Pemaparan Karbofuran Terhadap Gambaran Diameter Pulpa Putih Limpa Mencit (Mus musculus)= The Influence of Carbofuran Exposure Toward White Pulp Diameter of Spleen of Mice (Mus musculus)

Yohana Anggarasari, and Epy Muhammad Luqman, and Bambang Poernomo S., and Didik Handijatno, (2014) Pengaruh Pemaparan Karbofuran Terhadap Gambaran Diameter Pulpa Putih Limpa Mencit (Mus musculus)= The Influence of Carbofuran Exposure Toward White Pulp Diameter of Spleen of Mice (Mus musculus). Veterinaria Medika, 7 (2). pp. 100-105. ISSN 1979-1305

[img] Text (ARTIKEL)
karil 19 (pengaruh pemaparan karbofuran).pdf
Restricted to Registered users only

Download (1MB)
[img] Text (PEER REVIEW)
peerreview karil 19 (pengaruh pemaparan).pdf
Restricted to Registered users only

Download (953kB)

Abstract

The aim of the research was to observed the white pulp diameter of mice spleen histopathology through carbofuran exposured. Eighteen females Balb/C strain mice (Mus musculus) were aged 10 weeks and average body weights 30 grams has been used. The population of mice were divided into three groups i.e. P0, P1, and P2, each consist of six. Doses of each sample was 1 ml orally administered through gastric lavage, once a day, every morning, until day 10th. The P0 was given NaCl physiologic 0,9%, while both treatment groups were P1 and P2 given carbofuran doses 0,0208 and 0,0417 mg/kg of body weight, respectively. All of mices were sacrificed on day 12th, and followed through necropsy to observed the spleen. After that, the spleen histopathology was carried out in hematoxylin eosin (HE) stained. The spleen histopathology observation was carried out through light microscope at 200 times of magnification. The spleen histopathology examination was done to measure the average diameter of white pulp. The white pulp average was analyzed by F test of ANOVA with SPSS 16.0 for Windows program. The result showed that there was a significantly difference between both control and treatment groups (p<0,05). However, carbofuran exposure reduced the white pulp diameter of spleen of mice.

Item Type: Article
Uncontrolled Keywords: white pulp diameter, carbofuran
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF756.5-769.5 Special preclinical sciences, Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology
Divisions: 06. Fakultas Kedokteran Hewan
Peer Review
Creators:
CreatorsEmail
Yohana Anggarasari, UNSPECIFIED
Epy Muhammad Luqman, UNSPECIFIED
Bambang Poernomo S., UNSPECIFIED
Didik Handijatno, UNSPECIFIED
Depositing User: Ika Rudianto
Date Deposited: 20 Jul 2017 16:57
Last Modified: 20 Jul 2017 16:57
URI: http://repository.unair.ac.id/id/eprint/59237
Sosial Share:

Actions (login required)

View Item View Item