PROTECTIVE EFFECT OF Spirulina platensis ON HISTOPATHOLOGICAL CHANGES OF RENAL CORTEX OF PHYSICAL-STRESSED RAT (Rattus norvegicus)

AISYAH SURYANINGRUM, 061211132048 (2016) PROTECTIVE EFFECT OF Spirulina platensis ON HISTOPATHOLOGICAL CHANGES OF RENAL CORTEX OF PHYSICAL-STRESSED RAT (Rattus norvegicus). Skripsi thesis, Universitas Airlangga.

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Abstract

This research aimed to determine the protective effect of Spirulina platensis on histopathological changes of renal cortex of physical-stressed rat (Rattus norvegicus). Twenty male rats were divided into five groups (C –, C +, T 1, T 2, T 3) and treated for 35 days. C – were administered 2 ml CMC-Na 0,5%, C + were treated excessive physical exercise (swimming) for one hour/day, T1 were administered 300 mg/kg bw Spirulina platensis extract + one hour of excessive physical exercise (swimming)/day, T2 were administered 600 mg/kg bw Spirulina platensis extract + one hour of excessive physical exercise (swimming)/day and T3 were administered 1200 mg/kg bw Spirulina platensis extract + one hour of excessive physical exercise (swimming)/day. The histopathological features of renal cortex were examined using Modified Klopfleisch Scoring method. The obtained data analyzed with Kruskal-Wallis test and Mann-Whitney test. The result showed that Spirulina platensis extract could protect histopathological changes of renal cortex of physical-stressed rat (Rattus norvegicus). The dose of 600 mg/kg bw Spirulina platensis extract could protect renal cortex of physical-stressed rat (Rattus norvegicus). The antioxidants of Spirulina platensis that scavenge the active radicals to suppress chain initiation and/or break the chain propagation reactions.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH. 167/17 Sur p
Uncontrolled Keywords: Spirulina platensis, Physical-Stressed, Renal Cortex.
Subjects: Q Science > QL Zoology > QL1-991 Zoology
Q Science > QP Physiology > QP501-801 Animal biochemistry
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM/NIDN
AISYAH SURYANINGRUM, 061211132048UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorMas'ud Hariadi, Prof., drh., M.Phill., Ph.D.UNSPECIFIED
ContributorDjoko Legowo, drh., M.Kes.UNSPECIFIED
Depositing User: Mrs Nadia Tsaurah
Date Deposited: 24 Aug 2017 18:04
Last Modified: 24 Aug 2017 18:04
URI: http://repository.unair.ac.id/id/eprint/60902
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