EFEK EKSTRAK Spirulina platensis TERHADAP GAMBARAN HISTOPATOLOGI HEPAR TIKUS PUTIH ( Rattus Norvegicus ) JANTAN DALAM KEADAAN STRESS OXIDATIF

YOHANA YEKTI PIWI, 061211133072 (2016) EFEK EKSTRAK Spirulina platensis TERHADAP GAMBARAN HISTOPATOLOGI HEPAR TIKUS PUTIH ( Rattus Norvegicus ) JANTAN DALAM KEADAAN STRESS OXIDATIF. Skripsi thesis, Universitas Airlangga.

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Abstract

The objective of this research is to identify the effect of Spirulina platensis extract to histopatology description of white male rats (Rattus norvegicus) in oxidative stress with swimming in 1 hour for 35 days. This research uses 20 twomonth- old white male rats with 150 – 200 gram in average. Those rats are divided into 5 groups: (1) negative control group which is given 1 % Na-CMC, (2) positive control group which is treated swimming for an hour in 28 days, (3) first treatment (P1) group which is given 300 mg/kg BW Spirulina platensis then they swim for an hour, (4) second treatment group (P2) which is given 600 mg/kg BW Spirulina platensis then they swim for an hour, (5) third treatment group (P3) which is given 1200 mg/kg BW Spirulina platensis then they swim for an hour. In the end of the experiment, all rats are euthanized and their livers are taken for scoring. This research result shows that Spirulina platensis extract can improve white male rats liver histopatology in oxidative stress. These result show that Spirulina platensis extract could provide a significant protection from stress oksidative with 300 mg/ kg body weight, per oral.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH. 187/17 Piw e
Uncontrolled Keywords: spirulina plantesis, white male rats, liver, oxidative stress
Subjects: Q Science > QL Zoology > QL1-991 Zoology
Q Science > QP Physiology > QP501-801 Animal biochemistry
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM/NIDN
YOHANA YEKTI PIWI, 061211133072UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorNove Hidajati, Dr., drh., M.Kes.UNSPECIFIED
ContributorSri Mulyati, Dr., drh., M.Kes.UNSPECIFIED
Depositing User: Mrs Nadia Tsaurah
Date Deposited: 29 Aug 2017 19:35
Last Modified: 29 Aug 2017 19:35
URI: http://repository.unair.ac.id/id/eprint/61091
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