Basaria Margaretha Rumahorbo, dr (2017) PERBEDAAN KADAR FIBRINOGENPADA PPOK EKSASERBASI AKUT DAN PPOK STABIL DI POLI ASMA / PPOK RSUD SOETOMO DAN RSUD SOEWANDI SURABAYA. Thesis thesis, Universitas Airlangga.
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Abstract
Chronic obstructive pulmonary disease as a chronic inflammatory diseases occur locally in the lung but also systemic impact. Chronic inflammation in COPD continues by increased levels of cytokines proinflamation both in the airway and in the blood of patients with COPD. Fibrinogen is a important protein in responding to the stimulus of the IL-6 in acute exacerbation and stable of COPD Examination of the levels of fibrinogen in blood of the patients with COPD is still underrated and less attention to be investigated. Whereas examination of fibrinogen easy and fast. So for this reason researches assess the importance of this research.This research to adopting differences levels of fibrinogen in acute exacerbation and stable of COPD. Objective The purpose of this study is to measure levels of fibrinogen in acute exacerbations and stable of COPD, to analyze the differences in levels of fibrinogen in acute exacerbations and stable of COPD, and to predict the prognosis of COPD based on the levels of fibrinogen. Methods This study was an observasional analytic study Subjects were patien with acute exacerbation and stable of COPD, seeking treatment in Dr Soetomo Hospital and Soewandi Hospital and meet the inclusion and exclusion criteria. Result Differences in levels of fibrinogen in acute excerbation and stable of COPD showed significant with (p = 0,002 < 0,05) with average higher in acute exacerbations of COPD. The average value of fibrinogen in COPD acute exacerbation 550,67 ± 108,31 and stable COPD with an average value 317,75 ± 46,615. Conclusion There are significant differences in levels of fibrinogen in acute exacerbation and stable of COPD
| Item Type: | Thesis (Thesis) | |||||||||
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| Additional Information: | KKA KK PPDS.PKR 03/17 Rum p | |||||||||
| Uncontrolled Keywords: | Chronic obstructive pulmonary disease, acute exacerbation and stable of COPD, fibrinogen | |||||||||
| Subjects: | R Medicine | |||||||||
| Divisions: | 01. Fakultas Kedokteran > Ilmu Pulmonologi dan Ilmu kedokteran Respirasi | |||||||||
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| Depositing User: | Unnamed user with email indah.fatma@staf.unair.ac.id | |||||||||
| Date Deposited: | 06 Sep 2017 18:26 | |||||||||
| Last Modified: | 06 Sep 2017 18:26 | |||||||||
| URI: | http://repository.unair.ac.id/id/eprint/61329 | |||||||||
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