Antimalarial and antioxidant activity of phenolic compounds isolated from Erythrina crista-galli L.

Tjahjandarie, Tjitjik Srie and Pudjiastuti, Pratiwi and Saputri, Ratih Dewi and Tanjung, Mulyadi (2014) Antimalarial and antioxidant activity of phenolic compounds isolated from Erythrina crista-galli L. Journal of Chemical and Pharmaceutical Research, 6 (4). pp. 786-790. ISSN 0975-7384

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Abstract

Threephenolic compounds, phaseollidin (1), sandwicensin (2), and lonchocarpol A (3) had been isolated from the stem bark of Erythrina crista-galli. Their structures were established on the basis of spectroscopic evidence. Compounds 1–3 were evaluated for their antimalarial properties against Plasmodium palcifarum, showing their IC were 1.66, 1.83, and 1.69 µg/mL.The antioxidant activity of 1–3 against 2,2-diphenyl-1-picrylhydrazyl (DPPH), showing their IC50 were 209.4,305.6,and 1115.7 µM, respectively.

Item Type: Article
Uncontrolled Keywords: Erythrina crista-galli, Phenolic compound, Antimalarial, Antioxidant
Subjects: Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsEmail
Tjahjandarie, Tjitjik SrieUNSPECIFIED
Pudjiastuti, PratiwiUNSPECIFIED
Saputri, Ratih DewiUNSPECIFIED
Tanjung, MulyadiUNSPECIFIED
Depositing User: Mr Akhmad Nurfizal Reza
Date Deposited: 12 Oct 2017 20:26
Last Modified: 12 Oct 2017 20:26
URI: http://repository.unair.ac.id/id/eprint/63035
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