Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities

Tjahjandarie, Tjitjik Srie and Tanjung, Mulyadi (2015) Phenolic compounds from the stem bark of Erythrina orientalis and their cytotoxic and antioxidant activities. Der Pharmacia Lettre Journal., 7 (1). pp. 206-211. ISSN 0975-413X

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Abstract

Two prenylated pterocarpans, phaseollin (1), shinpterocarpin (2) together with flavonoids, 4’-O-methyl licoflavanone (3), alpinumisoflavone (4), 8-prenyl daidzein (5), have been isolated from the stem bark of Erythrina orientalis. The structures of these compounds were determined based on UV, IR, HRESIMS, 1D and 2D NMR data. Compounds 1–5 were evaluated for their cytotoxic properties against P-388 cells, their IC values 2.55, 2.43,17.98, 4.31, and 5.82 µg/mL, respectively. Compounds 1, and 5 exhibited very high antioxidant activity against DPPH radical scavenging.

Item Type: Article
Uncontrolled Keywords: Pterocarpan, Flavonoid, Erythrina orientalis, Cytotoxic, Antioxidant.
Subjects: Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsEmail
Tjahjandarie, Tjitjik SrieUNSPECIFIED
Tanjung, MulyadiUNSPECIFIED
Depositing User: Mr Akhmad Nurfizal Reza
Date Deposited: 12 Oct 2017 22:41
Last Modified: 12 Oct 2017 22:41
URI: http://repository.unair.ac.id/id/eprint/63039
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