Synthesis pterocarpan compounds from Erythrina crista-galli L and their action towards Plasmodium falciparum

Tjahjandarie, Tjitjik Srie and Saputri, Ratih Dewi and Tanjung, Mulyadi (2015) Synthesis pterocarpan compounds from Erythrina crista-galli L and their action towards Plasmodium falciparum. Journal of Chemical and Pharmaceutical Research, 7 (1). pp. 666-670. ISSN 0975-7384

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Official URL: http://www.jocpr.com/abstract/synthesis-pterocarpa...

Abstract

Synthesis of the naturally occurred 3-acetyl sandwicensin(2) and 2,7- dibromosandwicensin(3)was carried out by acetylation and bromination reaction, respectively. The pterocarpan synthesized in this study was andwicensin(1) isolated from stem bark of Erythrina crista galli L. Their structures were established on the basis of spectroscopic evidence. Compounds 1–3 were evaluated for their antimalarial properties against Plasmodium palcifarum, showing their IC were 1.83, 34.81 and 12.9 µg/mL, respectively.

Item Type: Article
Uncontrolled Keywords: 3-acetyl sandwicensin, 2,7-dibromosandwicensin, acetylation reaction, bromination reaction, antimalarial activity.
Subjects: Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsEmail
Tjahjandarie, Tjitjik SrieUNSPECIFIED
Saputri, Ratih DewiUNSPECIFIED
Tanjung, MulyadiUNSPECIFIED
Depositing User: Mr Akhmad Nurfizal Reza
Date Deposited: 12 Oct 2017 23:26
Last Modified: 12 Oct 2017 23:26
URI: http://repository.unair.ac.id/id/eprint/63040
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