UJI AKTIVITAS ANTASIDA DAN ANTIFLATULEN SEDIAAN SIRUP EKSTRAK ETANOL 70% KENINGAR (Cinnamomum zeylanicum Bl.), JAHE MERAH (Zingiber officinale Rosc. var rubrum) DAN DAUN CENGKEH (Syzygium aromaticum (L.) Merr. & Perry.) SECARA IN VITRO

AGNES ARNITA MAHARANI, 051211133090 (2017) UJI AKTIVITAS ANTASIDA DAN ANTIFLATULEN SEDIAAN SIRUP EKSTRAK ETANOL 70% KENINGAR (Cinnamomum zeylanicum Bl.), JAHE MERAH (Zingiber officinale Rosc. var rubrum) DAN DAUN CENGKEH (Syzygium aromaticum (L.) Merr. & Perry.) SECARA IN VITRO. Skripsi thesis, Universitas Airlangga.

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Abstract

Antacid are used widely for the relief of acid peptic diseases. Nowadays, antacid drugs have many side effects. Considering the side effects of antacids, traditional herbal medicine should be able to investigated as an alternative for the treatment of acid peptic diseases. Antacid usually are used in combination with antiflatulent. The present study investigates the antacid and antiflatulent activities of syrup formulations from Cinnamomum zeylanicum Bl., Zingiber officinale Rosc. var rubrum and Syzygium aromaticum (L.) Merr. & Perry 70% Ethanol Extract. Antacid and antiflatulent activities was evaluated using Vatier’s modified artificial stomach model and Rezak’s method, respectively. There were three different syrup formulations from 70% ethanol extract of Cinnamomi Zeylanici Cortex, Zingiberis Officinalis Var Rubrum Rhizoma and Syzygii Aromatici Folium with ratio of 5%: 2.5%: 2.5% (F1), 2.5%: 5%: 2.5% (F2) and 2.5%: 2.5%: 5% (F3). The result of antacid activity showed that formula 1 gave acid neutralization effect during 87.06 ± 2.21 minutes, formula 2 during 90.59 ± 1.43 minutes and formula 3 during 72.12 ± 1.74 minutes. The result of antiflatulent activity showed that formula 1 gave antifoaming action with the residual of foam level of 1.3 ± 0.1 cm, formula 2 of 1.2 ± 0,1 cm and formula 3 of 1.2 ± 0.1 cm. All treatments showed significant result for antacid and antiflatulent activities (p<0.05) when compared with negative control groups.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK2 FF.FT.13/17 Mah u
Uncontrolled Keywords: Cinnamomum zeylanicum Bl., Zingiber officinale Rosc. var rubrum, Syzygium aromaticum (L.) Merr. & Perry, Antacid, Antiflatulent.
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsEmail
AGNES ARNITA MAHARANI, 051211133090UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorSukardiman, Prof., Dr., M.S, Apt.UNSPECIFIED
ContributorHerra Studiawan, Drs., M.S, Apt.UNSPECIFIED
Depositing User: Mr Binkol1 1
Date Deposited: 28 Dec 2017 19:00
Last Modified: 17 Jan 2018 19:56
URI: http://repository.unair.ac.id/id/eprint/65107
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