PENGARUH KADAR KOPOLIMER ASAM METAKRILAT TIPE L SEBAGAI MATRIKS TERHADAP PROTEKSI SUHU Lactobacillus casei SAAT MIKROENKAPSULASI (Metode Spray Drying Suhu Inlet 120 ºC)

KARINA, 051311133161 (2017) PENGARUH KADAR KOPOLIMER ASAM METAKRILAT TIPE L SEBAGAI MATRIKS TERHADAP PROTEKSI SUHU Lactobacillus casei SAAT MIKROENKAPSULASI (Metode Spray Drying Suhu Inlet 120 ºC). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Microparticle was efficient method to protect probiotic bacteria from extreme conditions. Microencapsulation using suitable technique and matrix can keeps the probiotics active through the gastrointestinal tract and release them in their target organ. Lactobacillus casei was made into microparticle by spray drying method in air inlet temperature 120 °C with three different concentration of methacrylic acid copolymer L type. Three different formulas were named formula I, formula II, formula III with 0,5%; 0,75%; and 1,0% concentration of matrix. Physical characteristic and protection test were performed in all formula. The result showed that microparticles have unspherical shape, wrinkle, but non-porous. The particle size increased but moisture content decreased with increasing methacrylic acid copolymer L type concentration. Protection of probiotic microparticles increased with increasing methacrylic acid copolymer L type concentration but statistically, no significant difference showed between each formula with other formulas (p>0,05)

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.F. 04-17 Kar p
Uncontrolled Keywords: Microparticle, methacrylic acid copolymer L type, protection, microencapsulation, spray drying, probiotic, Lactobacillus casei.
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsNIM/NIDN
KARINA, 051311133161UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorH. Sugiyartono, Dr., Apt., M.S.UNSPECIFIED
ContributorWidji Soeratri, Prof. Dr., Apt. DEAUNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 01 Nov 2017 02:28
Last Modified: 01 Nov 2017 02:28
URI: http://repository.unair.ac.id/id/eprint/65400
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