PENGARUH KADAR KOPOLIMER ASAM METAKRILAT TIPE L SEBAGAI MATRIKS MIKROPARTIKEL PADA DAYA PROTEKSI Lactobacillus casei TERHADAP ASAM LAMBUNG (Dibuat dengan Metode Spray Drying Suhu Inlet 120 ºC)

AYUN DEWI RAHAYU, 051311133141 (2017) PENGARUH KADAR KOPOLIMER ASAM METAKRILAT TIPE L SEBAGAI MATRIKS MIKROPARTIKEL PADA DAYA PROTEKSI Lactobacillus casei TERHADAP ASAM LAMBUNG (Dibuat dengan Metode Spray Drying Suhu Inlet 120 ºC). Skripsi thesis, UNIVERSITAS AIRLANGGA.

[img]
Preview
Text (abstrak)
FF.F. 11-17 Rah p abstrak.pdf

Download (34kB) | Preview
[img] Text (fulltext)
FF.F. 11-17 Rah p fulltext.pdf
Restricted to Registered users only until 2 November 2020.

Download (2MB) | Request a copy
Official URL: http://lib.unair.ac.id

Abstract

Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. The bacteria was widely used as probiotic is Lactobacillus casei. Lactobacillus casei is not resistant to acidic conditions in stomach but has an intestinal action target. Microparticle delivery system are designed to protect Lactobacillus casei from acidic conditions and release them in their action target. Probiotic microparticles was made by spray drying method in 120 oC inlet temperature with different concentration of methacrylic acid copolymer L type as matrix. Three different formulas are formula I, formula II, and formula III with 0,50%; 0,75%; and 1,00% concentration methacrylic acid copolymer L type. Protection test from acidic condition were performed in all formula. The result showed that increasing methacrylic acid copolymer L type concentration can increase Lactobacillus casei protection from gastric condition. The highest protection was obtained by formula III. Data protection test was analyzed using One- Way ANOVA and showed there was significant different only with formula I.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.F. 11-17 Rah p
Uncontrolled Keywords: Lactobacillus casei, methacrylic acid copolymer L type, microparticle, probiotic
Subjects: R Medicine > RM Therapeutics. Pharmacology
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsEmail
AYUN DEWI RAHAYU, 051311133141UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorSugiyartono, Dr. H., Apt., MS.UNSPECIFIED
ContributorDwi Setyawan, Dr., Ssi.,M.Si.,Apt.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 01 Nov 2017 16:14
Last Modified: 01 Nov 2017 16:14
URI: http://repository.unair.ac.id/id/eprint/65410
Sosial Share:

Actions (login required)

View Item View Item