AKTIVITAS ANTIBAKTERI MIKROSFER NISIN MATRIKS ALGINATGELATIN (2,5 : 0,5)% DALAM MEDIA DAPAR SITRAT pH 4,5 (Bakteri Uji Staphylococcus aureus ATCC 6538)

ANGGRIANI LIDYA NINGSIH, 051311133095 (2017) AKTIVITAS ANTIBAKTERI MIKROSFER NISIN MATRIKS ALGINATGELATIN (2,5 : 0,5)% DALAM MEDIA DAPAR SITRAT pH 4,5 (Bakteri Uji Staphylococcus aureus ATCC 6538). Skripsi thesis, Universitas Airlangga.

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Abstract

The study was to investigate antibacterial activity profile of microsphere nisin using alginate-gelatin (2,5 : 0,5)% as matrix. The antibacterial activity test was performed by diffusion method using bacteria Staphylococcus aureus ATCC 6538. Antibacterial activity of microsphere nisin in citric buffer pH 4,5 + 0,05 as medium shown by inhibitory zone. By these results, we had antibacterial activity profile of nisin in microsphere. Profile antibacterial activity of the nisin microsphere obtained almost constant until sixth hour. The linear regression equation obtained from antibacterial activity of gentamicin sulfate is y = 5,7859x + 8,5203 with linear coefficient 0,9781. Inhibitory zone by microsphere nisin is intrapolation to linear regression. The results had an antibacterial activity equivalence of nisin in microsphere to gentamicin sulfate against Staphylococcus aureus ATCC 6538. They were 24,79 ppm (first hour), 4,68 ppm (second hour), 6,76 ppm (third hour), 6,92 ppm (fourth hour), 8,51 ppm (fifth hour) and 9,33 ppm (sixth hour)

Item Type: Thesis (Skripsi)
Additional Information: KKB KK2 FF.F.28/17 Nin m
Uncontrolled Keywords: Nisin, Microsphere, Antibacterial Activity.
Subjects: R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsNIM/NIDN
ANGGRIANI LIDYA NINGSIH, 051311133095UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorTutiek Purwanti, Dra. , Apt., M.SiUNSPECIFIED
ContributorTristiana Erawati M, Dr. ., M.Si., Apt.UNSPECIFIED
Depositing User: Mr Binkol2 2
Date Deposited: 27 Dec 2017 19:35
Last Modified: 27 Dec 2017 19:35
URI: http://repository.unair.ac.id/id/eprint/65476
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