Prevotella intermedia and Porphyromonas gingivalis in dental caries with periapical granuloma

Risya Cilmiaty and Afiono Agung Prasetyo and Khilyat Ulin Nur Zaini and Mandojo Rukmo and Suhartono Taat Putra and Widya Asmara (2013) Prevotella intermedia and Porphyromonas gingivalis in dental caries with periapical granuloma. Dental Jurnal (Majalah Kedokteran Gigi), 45 (4). ISSN 1978 - 3728

[img] Text
Majalah terakreditasi 7.pdf
Restricted to Registered users only

Download (343kB) | Request a copy
[img] Text
Majalah 7.pdf
Restricted to Registered users only

Download (492kB) | Request a copy

Abstract

Background: Dental caries with necrotic pulp is a multifactorial disease that attacks enamel involving tooth pulp. The anaerobic bacteria infection in the pulp chamber could induce the formation of periapical granuloma. However, the presence of the most frequently anaerobic bacteria identified in apical periodontitis, Porphyromonas gingivalis and Prevotella intermedia, in periapical granuloma have not been confirmed. Purpose: The aims of study were to determine the presence of Porphyromonas gingivalis and Prevotella intermedia in dental caries with necrotic pulp and to determine its relation to periapical granuloma. Methods: Thirty-six patients of dental caries with necrotic pulp in Dr. Moewardi General Hospital in Surakarta, Indonesia were involved and classified into two groups, the group of patients with periapical granuloma and the group of patients without periapical granuloma. The caries tooth was extracted, and the chronic periapical tissue was swabbed and cultured on blood agar medium in anaerobic condition. The bacterial DNA was extracted from the positive cultures and subjected for Polymerase Chain Reaction (PCR). Results: Periapical granuloma was more likely found in women (OR 5.5, 95% CI=1.277-23.693; RR 2.5, 95% CI= 1.025-6.100). Black colonies bacteria were associated with periapical granuloma (OR 2.2, 95% CI=0.517-9.594; RR 1.5, 95% CI=0.655-3.623). Porphyromonas gingivalis and Prevotella intermedia were detected in group with or without periapical granuloma, however, only Prevotella intermedia was associated with periapical granuloma (OR 1.6, 95% CI=0.418-5.903; RR 1.3, 95% CI=0.653-2.393). Conclusion: The presence of Porphyromonas gingivalis and Prevotella intermedia in periapical granuloma were confirmed, however, only Prevotella intermedia were associated with periapical granuloma. Key words: Dental caries, necrotic pulp, periapical granuloma, Prevotella intermedia, Porphyromonas gingivalis abstrak Latar belakang: Karies

Item Type: Article
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Concervative
Creators:
CreatorsNIM/NIDN
Risya CilmiatyUNSPECIFIED
Afiono Agung PrasetyoUNSPECIFIED
Khilyat Ulin Nur ZainiUNSPECIFIED
Mandojo RukmoUNSPECIFIED
Suhartono Taat PutraUNSPECIFIED
Widya AsmaraUNSPECIFIED
Depositing User: Rudy Febiyanto
Date Deposited: 09 Nov 2017 18:02
Last Modified: 09 Nov 2017 18:02
URI: http://repository.unair.ac.id/id/eprint/65772
Sosial Share:

Actions (login required)

View Item View Item