POTENSI EKSTRAK BUAH PARE (Momordica charantia L.) TERHADAP JUMLAH SEL LEYDIG DAN HORMON TESTOSTERON MENCIT (Mus Musculus) JANTAN

FARADILLAH HAPSARI DWI PUTRI, 061311133199 (2017) POTENSI EKSTRAK BUAH PARE (Momordica charantia L.) TERHADAP JUMLAH SEL LEYDIG DAN HORMON TESTOSTERON MENCIT (Mus Musculus) JANTAN. Skripsi thesis, Universitas Airlangga.

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Abstract

The active compound in bitter melon, i.e., flavonoid, is allegedly inhibiting the formation of testoterone by Leydig cell. The aim of the research was investigating the Leydig cell and testoterone level due to the addition of bitter melon extract (Momordica charantia L.). This research was conducted on December 2016 at the Animal Testing Lab of Faculty of Veterinary Medicine Universitas Airlangga, while the production of histopathology preparations was at the pathology laboratory of Universitas Airlangga Surabaya, and the execution of testosterone level test was at Balai Besar Laboratorium Kesehatan Surabaya. The utilized research design was Completely Randomized Design, exploiting 20 male house mice which are divided into four experimental groups of 5 male house mice each. Each group had given the treatments of bitter melon extract of 23mg/kgBB, 35mg/kgBB, 45,5mg/kgBB, while the control group had given the drug solvent of CMC Na 1%, which is conducted by utilizing feeding needles. In the 41st day, the male house mice were being euthanized by cervical dislocation. The Leydig cells could be observed by utilizing 400x microscope zoom, while the testosterone was examined utilizing Enzym Linken Immunosorbent Assay (ELISA). The research result demonstrated that the bitter melon extract (Momordica charantia L.) addition could decrease the Leydig cells and the testosterone level.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH.411/17 Put p
Uncontrolled Keywords: Bitter melon extract, Leydig cells, testosterone.
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsEmail
FARADILLAH HAPSARI DWI PUTRI, 061311133199UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorWurlina, Prof. Dr., drh., M.S.UNSPECIFIED
ContributorBenjamin Christoffel Tehupuring, Dr., drh., M.Si.UNSPECIFIED
Depositing User: Mr Binkol1 1
Date Deposited: 29 Dec 2017 16:19
Last Modified: 29 Dec 2017 16:19
URI: http://repository.unair.ac.id/id/eprint/66006
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