UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BELIMBING WULUH (Averrhoa bilimbi) TERHADAP Salmonella typhi

Margaretha Nathania, NIM011311133190 (2017) UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN BELIMBING WULUH (Averrhoa bilimbi) TERHADAP Salmonella typhi. Skripsi thesis, Universitas Airlangga.

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Abstract

Introduction: Medicinal plants contribute to human’s health and well -being. People use medicinal plants as traditional medicine for generations. One of the folk medicine that is easy to find , yet has beneficial effect and low cost is Averrhoa bilimibi . A. bilimbi or ‘ Belimbing Wuluh ’ in Indonesian which are a native Indonesia’s plant, is now cultivated in many countries . It is used as a treatment for cough, fever, mumps, bilious colic, stomach ache, etc. Many studies have proven that A.bilimbi extract has antidiabetic, antimicrobial, antiinflammatory , cytotoxic , antioxidant , and infert ility effect . Nowadays , many bacteria are resistant to antibiotic. Salmonella typhi which causes typhoid fever is resistant to multidrug s: ampicillin, chloramphenicol, cotrimoxazole and less sensitive against quinolones such as ciprofloxacin. To avoid fur ther resistance, traditional medicine is needed. The present study was carried out to determine the in vitro antibacterial activity of ethanol extract of Averrhoa bilimbi leaves against Salmonella typhi. Methods: This study was based on laboratory experimental. The samples wereethanol extract of Averrhoa bilimbi leaves and Salmonella typhi . A. bilimbi leaves were from Balai Materia Medika . The et hanol extraction was performed at Pharmacognosy and Phytochemistry Laboratory Faculty of Pharmacy Universitas Airlangga . S. typhi was from Microbiology Laboratory Faculty of Medicine Airlangga Univers ity . Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values were determined by dilution method. The concentrations used in determination for MIC were 500mg/ml, 250mg/ml, 125mg/ml, 62. 5mg/ml, 31. 25mg/ml, and 15.625mg/ml. The MBC value were determined by suspension streaking from Mueller -Hinton broth to nutrient agar plate.The result was analyzed by description method. Results :The MIC value could not be determined due to turbidity of the extract and t he MBC value was at 500mg/ml. Conclusion :Ethanol extract of Averrhoa bilimbi leaves have antibacterial activ ity against Salmonella typhi . MIC of ethanol extract of Averrhoa bilimbi leaves against Salmone lla typhi c ould not be determined. MBC of ethanol extract of Averrhoa bilimbi leaves against Salmonella typhi was at 500mg/ ml.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.31/17 Nat u
Uncontrolled Keywords: Averrhoa bilimbi– Salmonella typhi – antibacterial – dilution method
Subjects: R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsNIM/NIDN
Margaretha Nathania, NIM011311133190NIM011311133190
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorEddy Bagus Wasito, Prof. Dr. , dr., MS., Sp. MK(K)UNSPECIFIED
ContributorNurina Hasanatuludhiyah, dr., M.SiUNSPECIFIED
Depositing User: Mr Binkol2 2
Date Deposited: 01 Jan 2018 21:33
Last Modified: 01 Jan 2018 21:33
URI: http://repository.unair.ac.id/id/eprint/66195
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