FAKTOR RISIKO TUBERKULOSIS MILIER PADA ANAK DI RSUD DR SOETOMO TAHUN 2010-2015

Clarissa Cita Magdalena, 011311133176 (2016) FAKTOR RISIKO TUBERKULOSIS MILIER PADA ANAK DI RSUD DR SOETOMO TAHUN 2010-2015. Skripsi thesis, Universitas Airlangga.

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Abstract

Introduction: Miliary tuberculosis (TB) arises from the dissemination of the Mycobacterium tuberculosis bacteria into multiple organs, resulting in severe clinical symptoms and complications, including death. The mortality rate is still high, therefore identifying risk factors for miliary TB is important. This study analyzed the association of several proposed risk factors of miliary TB in children. Methods: A case-control study of children (0-14 years old) with miliary TB was conducted in Dr. Soetomo Hospital from 2010 to 2015. Data were taken from medical records. Cases were defined as children diagnosed with miliary TB, and controls as children diagnosed with pulmonary TB with score ≥ 6. Exclusion criteria were incomplete medical records. Cases were taken from total population; controls were taken using purposive sampling with case-control ratio of 1:1. Factors analyzed were age, nutritional status, BCG immunization status, and history of contacts. Statistical analysis was done with Chi-square and logistic regression. P value of < 0.05 was considered statistically significant. Results: Seventy-two children were analyzed, 36 cases and 36 controls. Nutritional status was found significantly associated with miliary TB in children (p = 0.018, OR 3.182, 95%CI 1.206 – 8.398) in both bivariate and multivariate analysis. The probability of a child developing miliary TB if the nutritional status is moderate or severe undernutrition is 76.09%. Other factors such as age, BCG immunization status, and history of contacts were not significantly associated with miliary TB. Conclusion: Nutritional status is significantly associated with miliary TB in children, and moderate or severe undernutrion increases the risk for developing miliary TB.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.165/17 Mag f
Uncontrolled Keywords: Miliary tuberculosis, children, case-control, risk factors
Subjects: R Medicine > RC Internal medicine > RC306-320.5 Tuberculosis
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsEmail
Clarissa Cita Magdalena, 011311133176UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorRetno Asih Setyoningrum, dr., SpA(K)UNSPECIFIED
ContributorH. Budi Utomo, Dr., dr., M.KesUNSPECIFIED
Depositing User: Mr Binkol1 1
Date Deposited: 30 Dec 2017 16:16
Last Modified: 30 Dec 2017 16:16
URI: http://repository.unair.ac.id/id/eprint/66334
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