SUBTIPE MOLEKULAR INTRINSIK PASIEN KANKER PAYUDARA YANG RAWAT JALAN di POSA RSUD Dr. SOETOMO SURABAYA pada TAHUN 2015

Tantri Adhiatma Lukitaningrum S, 011311133227 (2017) SUBTIPE MOLEKULAR INTRINSIK PASIEN KANKER PAYUDARA YANG RAWAT JALAN di POSA RSUD Dr. SOETOMO SURABAYA pada TAHUN 2015. Skripsi thesis, Universitas Airlangga.

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Abstract

Introduction : Breast cancer is the second most common over all cancer (1.670.000 new cases) and rank as the fifth (522.000 deaths) cause of death over all cancer in the world in 2012. For Indonesian women, breast cancer rank as second with highest incidence rate (33.7-47 per 100.000 population) after cervix cancer with 19.750 death cases (Youlden, 2014) . Prognosis and treatment respond therapy can be affected by breast cancer‟s intrinsic molecular subtypes . Objective : To determine the distribution of the intrinsic molecular subtypes in breast cancer patients whose outpatient in POSA Dr. Soetomo Public Hospital in 2015. Method : A descriptive observational study research. Number of sampel 220 patients. Technique sampling is non random sampling. The data is secodary data. Research variables consist of patient‟s age, the expression of estrogen receptor, progesterone receptor, HER2/NEU receptor, and subtypes molecular intrinsic of cancer. Descriptive data analysis. Result : Most of breast cancer patients with category, 1) age group (40.5%) 40- 49 tahun, 2) estrogen receptor positive (66.8%), 3) progesterone receptor positive (70.5%), 3) HER2/NEU negative (60.9%), 4) subtipe molecular intrinsic Luminal (76.8%), 4) Subtype Luminal dan triple negative (40.2% dan 50%) on age group 40-49 years also subtype HER2/NEU enriched (46.7%) on age group 50-59 years. Conclusion : Most of breast cancer patients are on age group 40-49 years, estrogen and progesteron positive, HER2/NEU negative, subtype luminal. Subtype Luminal and triple negative are on age group 40-49 years also subtype HER2/NEU enriched on age group 50-59 years.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.131/17 Luk s
Uncontrolled Keywords: breast cancer, estrogen receptor , progesterone receptor, HER2/NEU receptor subtype molecular intrinsik
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsEmail
Tantri Adhiatma Lukitaningrum S, 011311133227UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorSusilowati Andajani, Dr. , dr., MSUNSPECIFIED
ContributorHeru Purwanto, dr. M.Epid., Sp.B(K)OnkUNSPECIFIED
Depositing User: Mr Binkol2 2
Date Deposited: 03 Jan 2018 01:00
Last Modified: 03 Jan 2018 01:00
URI: http://repository.unair.ac.id/id/eprint/66385
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