STUDI AKTIVITAS ANTIMALARIA SECARA IN VITRO TERHADAP PLASMODIUM FALCIPARUM PADA TANAMAN DARI SUKU LAURACEAE YANG TUMBUH DI KEBUN RAYA BALIKPAPAN, KALIMANTAN TIMUR

RIZA ROSITA MURIYANI, 051311133168 (2017) STUDI AKTIVITAS ANTIMALARIA SECARA IN VITRO TERHADAP PLASMODIUM FALCIPARUM PADA TANAMAN DARI SUKU LAURACEAE YANG TUMBUH DI KEBUN RAYA BALIKPAPAN, KALIMANTAN TIMUR. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Malaria is an infectious disease that caused by parasites of the Plasmodium family. Severe malaria is mainly caused by Plasmodium falciparum. The presence of resistance Plasmodiumparasite against antimalarial drugs, encourages the discovery of new chemical compounds for antimalarial agent.Exploration of medicinal plants from Balikpapan Botanical Garden has obtained Eusideroxylon zwageri, Alseodaphne elmeriandNeolitseacassiaefolia from Lauraceae family.These plants were extracted using n-hexane, dicloromethane, and methanol solvents gradually. Phytochemical screening was undertaken by TLC method on the extracts to investigate the presence of alkaloid, flavonoid, terpenoid, polifenol and antrakuinon. Antimalarial screening was performed by using ELISA-HRP II and microscopic. The results indicated that the DCM extract of Neolitsea cassiaefolia foliumshowed the highest inhibition in both ELISA-HRP II and microscopic methods with % inhibition of (73,93±1,34%) and (99,6±0,60%) respectively. The result of phytochemical screening suggested that DCM extract of Neolitseacassiaefolia folium contained terpenoid.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.FT. 55-17 Mur s
Uncontrolled Keywords: Plasmodium falciparum, HRP-II, ELISA, microscopic, antimalarial activity test, Neolitsea cassiaefolia, Eusideroxylon zwageri, Alseodaphne elmeri, Lauraceae.
Subjects: R Medicine > RC Internal medicine > RC31-1245 Internal medicine
R Medicine > RC Internal medicine > RC554-569.5 Personality disorders. Behavior problems Including sexual problems, drug abuse,suicide, child abuse
R Medicine > RM Therapeutics. Pharmacology
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM/NIDN
RIZA ROSITA MURIYANI, 051311133168UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorAty Widyawaruyanti, Dr., Msi., Apt.UNSPECIFIED
ContributorSuciati, S.Si, M.Phil., Ph.D.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 13 Nov 2017 20:30
Last Modified: 13 Nov 2017 20:30
URI: http://repository.unair.ac.id/id/eprint/66457
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