POLA RESISTENSI FLORA USUS SAPI TERHADAP ANTIBIOTIKA

Marischa Tita Thiono, 011311133105 (2017) POLA RESISTENSI FLORA USUS SAPI TERHADAP ANTIBIOTIKA. Skripsi thesis, Universitas Airlangga.

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Abstract

Introduction: Antimicrobial resistance is a serious threat to global public health worldwide. The use of antibiotics were common in human sectors, but the animal is not exeption. The increasing prevalence of antimicrobial resistance (AMR) urge the researcher to explore more about AMR, to provide the data for management of infection, and preventive activity for tackling AMR. This study aimed to explore the prevalence and correlation of antibiotic usage with AMR of gut flora on cattle. Methods: This study was a descriptive analytic. The data of antibiotic use was collected by quessionair and the susceptibility pattern of gut flora was conducted by swabbing rectal specimen of cattle from 3 center of cattle faram. The dominant flora was isolated by microbiological culture as standard procedure and tested by disk diffusion method as CLSI. Total 6 antibiotics disk were used in the laboratory test. The result is analyzed with description method. Results: Total 3 centers and 15 cattle was studied. The antibiotic use was as follow: beta-lactam antibiotic (penicillin, cloxacillin, ampicillin), tetracycline and aminoglycoside were identified among 5 cattles, tetracycline among 10 cattle and aminoglycoside among 10 cattles. Dominant gut flora of cattle showed the total 10 strains E coli, 3 strains Proteus vulgaris and 2 strains Proteus mirabilis. The pattern of susceptibility of gut dominant flora was as follow: sensitive against meropenem 93,3%, amoksisilin-klavulanat 86,6%, ceftazidime 86,6%, Tygecycline 100%, Cotrimoxazole 100%, and Amikacin 100%. The intermediate result were Meropenem (6.66%), Amoxicillin-clavulanate (12.66%), and Ceftazidime (12.66%). However, it is still sensitive to Tigecycline, Trimethoprim-sulfamethoxazol, and Amikacin. There not resistant straints for all isolates. Conclusion: There was any antibiotic usage in cattle farm in East Java, such as betalactam antibiotic, tetracycline and aminoglycoside. Most antibiotic were susceptible against gut bacterial flora. The antibiotic with result of intermediate were identified among meropenem, amoxicillin-clavulanic acid and ceftazidime.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.272/17 Thi p
Uncontrolled Keywords: Animal Gut flora, antimicrobial resistance, AMR, cattle farm
Subjects: R Medicine
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsNIM/NIDN
Marischa Tita Thiono, 011311133105UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorKuntaman, Prof. Dr., dr., MS., Sp.MK (K)UNSPECIFIED
ContributorDanti Nur Indiastuti, dr.,M.Ked.UNSPECIFIED
Depositing User: Mr Binkol1 1
Date Deposited: 31 Dec 2017 00:33
Last Modified: 31 Dec 2017 00:33
URI: http://repository.unair.ac.id/id/eprint/66645
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