EFEKTIFITAS CHLORHEXIDINE GLUCONATE 2 %, SODIUM HYPOCHLORITE 2,5 % DAN CHLORHEXIDINE CHLORIDE TERHADAP HAMBATAN AKTIFITAS ENZIM GLUCOSYLTRANSFERASE Lactobacillus acidophilus

Fahmi Mulya, 021418036307 (2017) EFEKTIFITAS CHLORHEXIDINE GLUCONATE 2 %, SODIUM HYPOCHLORITE 2,5 % DAN CHLORHEXIDINE CHLORIDE TERHADAP HAMBATAN AKTIFITAS ENZIM GLUCOSYLTRANSFERASE Lactobacillus acidophilus. Thesis thesis, Universitas Airlangga.

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Abstract

Background: Lactobacillus acidophilus produced extracellular enzymes that can improve the attachment to the dentin surface who known as enzyme glucosyltransferase (GTF). This enzym hydrolyze sucrose into glucose and fructose as the initial biofilm formation plays a role in the process of recolonisation. The solution of 2% chlorhexidine gluconate, 2.5% sodium hypochlorite (NaOCl) and chlorhexidine chloride is believed to inhibit the enzyme glucosyltransferase activity of the Lactobacillus acidophilus. Objective: To determine the effectiveness of the solution of 2% chlorhexidine gluconate, 2.5% sodium hypochlorite and chlorhexidine chloride against glucosyltransferase (GTF) Lactobacillus acidophilus. Materials and Methods: This study used the enzyme glucosyltransferase (GTF) from the supernatant of Lactobacillus achidophilus bacteria are divided into each of 6 different tubes to the observed activity in the formulation of chlorhexidine gluconate concentration of 2%, 2.5% NaOCl and chlorhexidine chloride. The entire sample was tested using High Performance Liquid Chromatography (HPLC) to view the activity of the enzyme glucosyltransferase (GTF) in all study groups. Statistical test using one-way ANOVA and LSD (p<0.005). Results: chlorhexidine chloride to the enzyme activity of glucosyltransferase (GTF) Lactobacillus acidophilus showed a significant difference (p<0.05) compared to 2% chlorhexidine gluconate and 2.5% NaOCl Conclusions: The ability of chlorhexidine chloride to inhibit the enzyme activity of glucosyltransferase (GTF) Lactobacillus acidophilus better than the 2.5% sodium hypochlorite and 2% chlorhexidine gluconate.

Item Type: Thesis (Thesis)
Additional Information: KKA KK PPDGS.KON.09/17 Mul e
Uncontrolled Keywords: Lactobacillus acidophilus, glucosyltransferase, chlorhexidine gluconate, NaOCl, chlorhexidine chloride
Subjects: R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Concervative
Creators:
CreatorsEmail
Fahmi Mulya, 021418036307UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorIra Widjiastuti, Dr., drg, M.Kes., Sp.KG(K)UNSPECIFIED
ContributorMandojo Rukmo, Prof. Dr., drg, M.Sc, Sp.KG(K)UNSPECIFIED
Depositing User: Mr Binkol1 1
Date Deposited: 31 Dec 2017 15:49
Last Modified: 31 Dec 2017 15:49
URI: http://repository.unair.ac.id/id/eprint/66890
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