GAMBARAN KLINIS STEVEN JOHNSON SYNDROME DAN TOXIC EPIDERMAL NECROLYSIS PADA PASIEN ANAK USIA 0 – 18 TAHUN DI INSTALASI RAWAT INAP RSUD DR. SOETOMO SURABAYA PERIODE 2013 - 2016

Annisa Fitriana, 011411131006 (2017) GAMBARAN KLINIS STEVEN JOHNSON SYNDROME DAN TOXIC EPIDERMAL NECROLYSIS PADA PASIEN ANAK USIA 0 – 18 TAHUN DI INSTALASI RAWAT INAP RSUD DR. SOETOMO SURABAYA PERIODE 2013 - 2016. Skripsi thesis, Universitas Airlangga.

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Abstract

Background: Steven Johnson Syndrome (SJS), Steven Johnson Syndrome (SJS)-Toxic Epidermal Necrolysis (TEN) overlap, dan Toxic Epidermal Necrolysis (TEN) are an hypersensitivity reaction mediated by immune-complex. The epidemiology of SJS, SJS-TEN overlap, and TEN in Indonesia are rare, but it can caused a life threatening complication especially in pediatric patients. Objectives: To obtain further information and understanding about clinical presentation of Steven Johnson Syndrome (SJS), Steven Johnson Syndrome (SJS) – Toxic Epidermal Necrolysis (TEN) overlap, and Toxic Epidermal Necrolysis (TEN) in pediatric patients aged of 0 to 18 years in inpatient care installation of Dr. Soetomo General Hospital Surabaya from 2013 to 2016. Methods: This is a retrospective descriptive study of pediatric patients aged of 0 to 18 years with Steven Johnson Syndrome (SJS), Steven Johnson Syndrome (SJS) – Toxic Epidermal Necrolysis (TEN) overlap, and Toxic Epidermal Necrolysis (TEN) in inpatient care installation of Dr. Soetomo General Hospital Surabaya from 2013 to 2016 with total sampling methods of 19 patient’s medical record. Results: From this research, the most common etiology of SJS, SJS – TEN overlap, and TEN in patient samples population is caused by acetaminophen drug – induced SJS, SJS – TEN overlap, and TEN (24%). Skin manifestation is the most common clinical manifestation as it is found in all patient samples. The most common comorbid which is found in patient samples population are malnutrition (31%) and conjungtivitis (31%). Conjungtivitis is also the most common complication that is found in patient samples population (67%). The average length of hospital course of patient samples is 11.6 days. Ten out of nineteen patients need to be consulted to other specialist (53%) and the most common consultation needed by patient is ophtalmologist consultation (80%). The most common theraphy given to the patients samples is stopping the administration of the culprit drug (79%).

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.360/17 Fit g
Uncontrolled Keywords: Steven Johnson Syndrome, Toxic Epidermal Necrolysis, Steven Jonson Syndrome in children, clinical presentation, etiology, clinical manifestation, comorbid, complication, therapy, consultation.
Subjects: R Medicine > RA Public aspects of medicine > RA1-1270 Public aspects of medicine > RA1190-1270 Toxicology. Poisons
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsNIM/NIDN
Annisa Fitriana, 011411131006UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorAnang Endaryanto, Dr. , dr., Sp.A (K)UNSPECIFIED
ContributorAfif Nurul Hidayati, Dr. , dr., Sp.KKUNSPECIFIED
Depositing User: Mr Binkol2 2
Date Deposited: 19 Feb 2018 17:18
Last Modified: 19 Feb 2018 17:18
URI: http://repository.unair.ac.id/id/eprint/68452
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