HUBUNGAN ANTARA STATUS RESEPTOR HORMONAL DENGAN DURASI LAKTASI PADA PASIEN KANKER PAYUDARA DI RSUD DR. SOETOMO

Afina Thara Pitaloka, 011411131122 (2017) HUBUNGAN ANTARA STATUS RESEPTOR HORMONAL DENGAN DURASI LAKTASI PADA PASIEN KANKER PAYUDARA DI RSUD DR. SOETOMO. Skripsi thesis, Universitas Airlangga.

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Abstract

Background: Breast cancer is the most common cancer in woman with a high percentage of new cases and highest mortality rate. Breast cancer is characterized by abnormal cell development, tissue invasion, and metastasize from the origin cell to other body parts. Breast cancer is affected by hormonal receptor status such as Estrogen Receptor (ER) and Progesteron Receptor (PR). Lactation is a metabolic and reproductive process of a woman in which mammary glands proliferate and produce milk. In 2016, WHO recommended exclusive duration of lactation for the first 6 months without food supplements and continues for up to 2 years. Objective: To analyze the correlation of hormonal receptor status and lactation duration of breast cancer patients in Dr. Soetomo General Hospital Methods: This research was designed in crosssectional which observe breast cancer patients in Poli Onkologi Satu Atap (POSA) RSUD Dr. Soetomo from 1 January 2017– 28 February 2017. Age, parity, age at first birth, and duration of lactation were examined in both case and control group. Results: These findings suggest that age, parity, and age at first birth had no significant difference value between duration of lactation equal to 18 months or more and duration of lactation less than 18 months (p= 0,931, p=0,354, p= 0,460). Duration of lactation equal to 18 months or more has higher percentage of ER+ and/or PR+ hormonal receptor status compared to ER- and PR- in breast cancer patients (OR= 9,412; CI 95% 3,402-26,037; p=0.001). Conclusion: Duration of lactation had significant difference with hormonal receptor status.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.327/17 Pit h
Uncontrolled Keywords: Breast cancer, Estrogen Receptor, Lactation, Progesteron Receptor.
Subjects: R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsEmail
Afina Thara Pitaloka, 011411131122UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorHeru Purwanto, dr, M.Epid, Sp.B(K)OnkUNSPECIFIED
ContributorEtty Hary Kusumastuti, dr, Sp.PA(K)UNSPECIFIED
Depositing User: Mr Binkol1 1
Date Deposited: 16 Jan 2018 20:45
Last Modified: 16 Jan 2018 20:45
URI: http://repository.unair.ac.id/id/eprint/68494
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