Efektivitas Pemberian Jus Buah Kersen (Muntingia calabura) terhadap Penurunan Kadar Gula Darah Mencit (Mus musculus) dengan Diabetes Melitus

RM Yusuf Aji Samudera Nurrobi, NIM011411131029 (2017) Efektivitas Pemberian Jus Buah Kersen (Muntingia calabura) terhadap Penurunan Kadar Gula Darah Mencit (Mus musculus) dengan Diabetes Melitus. Skripsi thesis, Universitas Airlangga.

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Abstract

Objective: The aim of this experiment is to evaluate the efficacy of Muntingia Calabura in decreasing blood glucose level in diabetic mice. Materials and Methods: Mice were induced with multiple low dose streptozotocin (40mg/kg) in 5 consecutive days by intraperitoneal injection. After 7 days of adaptation, Muntingia Calabura was given in 2.8 mg/20gBB and 5.6 mg/20gBB for 14 days. Administration of Muntingia calabura was compared with metformin 2 mg/20gBB. Blood samples were collected in day 0 and 14 to evaluate pre and post blood glucose level. Result: Administration of 5,6 mg/20gBB Muntingia calabura and metformin 2 mg/20gBB signifficantly reduce blood glucose level of diabetic mice. But, administration of 2,8 mg/20gBB Muntingia calabura does not significantly reduce blood glucose of diabetic mice. Muntingia calabura 5,6 mg/20gBB has 82,1% efectivity to reduce blood glucose level, lower than metformin 2 mg/20gBB that has 82,3% Conclusion: The administration of 5,6 mg/gBB Muntingia calabura has proven to be effective to reduce blood glucose level in diabetic mice but metformin 2 mg/20gBB is more efective.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK FK.PD.469/17 Nur e
Uncontrolled Keywords: Muntingia Calabura, Mus Musculus, Metformin, Diabetes Melitus, Streptozotocin
Subjects: H Social Sciences > HD Industries. Land use. Labor > HD58.7-58.95 Organizational behavior, change and effectiveness. Corporate culture
R Medicine > RC Internal medicine > RC475-489 Therapeutics. Psychotherapy
Divisions: 01. Fakultas Kedokteran
Creators:
CreatorsNIM/NIDN
RM Yusuf Aji Samudera Nurrobi, NIM011411131029NIM011411131029
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorMohammad Fathul Qorih, dr., Sp.KFR.UNSPECIFIED
ContributorHermina Novida, dr., Sp.PD., K-EMD.UNSPECIFIED
Depositing User: Mrs Nadia Tsaurah
Date Deposited: 04 Jan 2018 22:07
Last Modified: 04 Jan 2018 22:07
URI: http://repository.unair.ac.id/id/eprint/68770
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