EFFECT OF Polygonum minus LEAVES ETHANOL EXTRACT AS A PREVENTIVE AGAINST MERCURIC CHLORIDE TOXICITY IN HISTOLOGICAL FEATURES OF MICE (Mus musculus) TESTIS

MUHAMMAD RISTO AL ADIL ZULFAR, 061311133154 (2017) EFFECT OF Polygonum minus LEAVES ETHANOL EXTRACT AS A PREVENTIVE AGAINST MERCURIC CHLORIDE TOXICITY IN HISTOLOGICAL FEATURES OF MICE (Mus musculus) TESTIS. Skripsi thesis, Universitas Airlangga.

[img]
Preview
Text (ABSTRACT)
KKC KK KH 04 - 18 Zul e-Abstrak.pdf

Download (94kB) | Preview
[img] Text (FULLTEXT)
KKC KK KH 04 - 18 Zul e.pdf
Restricted to Registered users only until 8 March 2021.

Download (1MB) | Request a copy
Official URL: http://lib.unair.ac.id

Abstract

The purpose of this research are to prove the effect of Polygonum minus leaves ethanol extract as a preventive against mercuric chloride (HgCl2) toxicity in seminierous tubules epithelium thickness and spermatocyte cells count. This research use Completely Randomized Design with 20 male Balb/C mice divided into 5 groups and 4 mice each group. Treatment consisted of C- administered orally CMC Na 0.5% and aquadest only, C+ administered orally CMC Na 0.5%, T1 200 mg/kg bw, T2 400 mg/kg bw, T3 800 mg/kg bw Polygonum minus leaves extract administered orally then given 8 mg/kg bw HgCl2 solution after one hour. The research takes 7 days adaptation and 21 days treatment. Observations conducted by making histologic preparations of testicular organs, five seminiferous tubules observed from each replication to measure the epithelium thickness and count the spermatocyte cells. The data were analyzed with Analysis of Variance (Anova), and Duncan test. The result showed seminiferous tubules epithelium thickness have simillar data with the spermatocyte cells count but no significant (P>0.05) in all groups while there was a significant difference (P<0.05) for spermatocyte cells count data. The best result are shown from T1 group treated with 200 mg/kg bw Polygonum minus ethanol extract.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH 04/18 Zul e
Uncontrolled Keywords: Mercuric Chloride, Polygonum minus, Seminiferous tubules epithelium thickness, Spermatocyte cells
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM/NIDN
MUHAMMAD RISTO AL ADIL ZULFAR, 061311133154UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorHani Plumeriastuti, Dr., M.Kes., drh.UNSPECIFIED
ContributorSetiawan Koesdarto, Prof. Dr., M.Sc., drhUNSPECIFIED
Depositing User: Mrs. Djuwarnik Djuwey
Date Deposited: 07 Mar 2018 18:41
Last Modified: 07 Mar 2018 18:41
URI: http://repository.unair.ac.id/id/eprint/70454
Sosial Share:

Actions (login required)

View Item View Item