EKSPRESI MMP-1 DAN TGF-β1 SETELAH APLIKASI DENTIN BONDING BERBASIS HEMA

Mulia Rahmah, drg, 021518036318 (2018) EKSPRESI MMP-1 DAN TGF-β1 SETELAH APLIKASI DENTIN BONDING BERBASIS HEMA. Thesis thesis, Universitas Airlangga.

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Abstract

Dentin bonding is the material to attach the composite resin to dentine. The main composition is 2-hydroxyethyl methacrilate (HEMA). After polimerization, occured residual monomers which diffuse from dentinal tubuli to pulp can affected odontoblast. Objective: To analyze MMP-1 and TGF-β1 expression on odontoblast of complex dentin pulp of wistar rat tooth which was treated with dentin bonding HEMA dan HEMA murni. Methods: Maxillary first molar toot wistar rat was only bur prepared for 3 days (group 1), then HEMA 10 % was aplicated for 3 days (group 2). Dentin bonding HEMA was aplicated and polimerization light cured for 3 days (group 3). After aplication HEMA and dentin bonding HEMA the tooth was filled with RMGIC. The rat was sacrifised and maxillary resection on the define day for immunohistochemistry evaluation. Result: Expression MMP-1 on dentin bonding HEMA were lower than HEMA, expression TGF-β1 on dentin bonding HEMA were higher than HEMA. Conclusion : There were significant differences on expression MMP-1 dan TGF- β1 between dentin bonding HEMA and HEMA

Item Type: Thesis (Thesis)
Additional Information: KKA KK PPDGS KON 03/18 Rah e
Uncontrolled Keywords: Dentin bonding, HEMA, MMP-1, TGF-β1
Subjects: R Medicine > RK Dentistry > RK641-667 Prosthetic dentistry. Prosthodontics
Divisions: 02. Fakultas Kedokteran Gigi > Concervative
Creators:
CreatorsNIM/NIDN
Mulia Rahmah, drg, 021518036318UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorAri Subiyanto, drg., MKes., Sp.KG (K)UNSPECIFIED
Depositing User: Unnamed user with email indah.fatma@staf.unair.ac.id
Date Deposited: 19 Mar 2018 00:33
Last Modified: 19 Mar 2018 00:33
URI: http://repository.unair.ac.id/id/eprint/70957
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