TOLERAN PADA MENCIT NEONATUS BALB/c SETELAH PAPARAN ALERGEN PADA INDUK BUNTING (Kajian toleran terhadap ekspresi sitokin IL-2, IFN-

RISA ETIKA, 090810563D (2018) TOLERAN PADA MENCIT NEONATUS BALB/c SETELAH PAPARAN ALERGEN PADA INDUK BUNTING (Kajian toleran terhadap ekspresi sitokin IL-2, IFN-. Disertasi thesis, Universitas Airlangga.

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Abstract

Background : Allergy is a health problem that increasingly need attention. Prevention efforts still have not managed to improve the disease satisfactorily. Meanwhile in–utero prevention efforts based on immunologies comprehension remains unclear. Research on tolerance in newborn Balb/c mice after exposing with allergens on pregnant mice needs to be done. Aims : To explain the allergens exposure on pregnant Balb/c mice and its role to tolerance in newborn mice by measuring cytokines Th1, Th2, Treg and IgG-1, IgG-2a, IgG-2b, IgG3 subclass level and IgM, IgA, IgE. Methods : Research in Virology & Immunology Laboratory, Dept of Microbiology Veterinary Faculty Airlangga University. Experimental study post-test only control group design, using factorial design to asses the effect of allergens Mite, Cat Hair, Dog Hair, Chicken Albumin and Cow Milk Protein with low-dose and high dose on pregnant Balb/c and newborn mice to tested variables. Sixty Balb/c pregnant mices divided into intervention group and control. Blood sampling of pregnant Balb/c and newborn mice to assess Th1(IL-2, IFN-

Item Type: Thesis (Disertasi)
Additional Information: KKA KK Dis K 09/18 Eti t
Uncontrolled Keywords: allergen, pregnant Balb/c mice, newborn mice, tolerance
Subjects: R Medicine > RG Gynecology and obstetrics > RG1-991 Gynecology and obstetrics > RG500-991 Obstetrics > RG551-591 Pregnancy
Divisions: 09. Sekolah Pasca Sarjana > Ilmu Kedokteran
Creators:
CreatorsEmail
RISA ETIKA, 090810563DUNSPECIFIED
Contributors:
ContributionNameEmail
ContributorSubijanto Marto Sudarmo, Prof. Dr. , dr., SpA(K)UNSPECIFIED
Depositing User: Unnamed user with email indah.fatma@staf.unair.ac.id
Date Deposited: 22 Mar 2018 19:27
Last Modified: 22 Mar 2018 19:27
URI: http://repository.unair.ac.id/id/eprint/71200
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