The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis

Adam Widya, Wicaksono and Ernie Maduratna, Setiawatie and Mohamad Rubianto, Rubianto (2012) The Inhibition of Noni Fruit Extract (Morinda citrifolia L.) on The Growth of Porphyromonas gingivalis. Periodontic Journal, 4 (1). ISSN 2085-711X.

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Official URL: http://dentj.fkg.unair.ac.id/periodontic-journal-d...

Abstract

Background : Periodontitis is an inflammation on periodontal structure that caused by invasion microorganism. Among periodontitis’s types, chronic periodontitis is the most prevalent type and often associated with Porphyromonas gingivalis. Nowadays, herbal therapy is often used as antibacterial agent to inhibit microorganism’s growth. The herbs used in this research is noni fruit extract (Morinda citrifolia L.) that contain many antibacterial agent such as anthraquinone, saponin, and iridoid. Purpose : The aim of this research is to find the inhibition of noni fruit extract (Morinda citrifolia L.) on the growth of Porphyromonas gingivalis. Method : This research was done in vitro experiment using agar disc diffusion method. The extract was diluted into concentration of 100%, 50%, 25%, 12,5%, 6,25%, 3,12%, 1,56%, 0,78%, 0,39%, and 0,19%. The inhibitory zones were recorded in millimeters and analyzed using One Way ANOVA test. Result : The result showed that antibacterial activity of noni fruit extract was active on Porphyromonas gingivalis with Minimum Inhibitory Concentration (MIC) of 3,12% with average of inhibitory zone 8,21 mm. From statistical test showed that there were significant differences of inhibitory zone from each concentration. Conclusion : Noni fruit extract (Morinda citrifolia L.) could inhibit the growth of Porphyromonas gingivalis with Minimum Inhibitory Concentration (MIC) at 3,12%.

Item Type: Article
Uncontrolled Keywords: Noni, fruit, extract, (Morinda, citrifolia, L.), Porphyromonas, gingivalis, Minimum, Inhibitory, Concentration
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Periodontics
Creators:
CreatorsNIM/NIDN
Adam Widya, WicaksonoUNSPECIFIED
Ernie Maduratna, SetiawatieUNSPECIFIED
Mohamad Rubianto, RubiantoUNSPECIFIED
Depositing User: Rudy Febiyanto
Date Deposited: 18 Jul 2018 19:11
Last Modified: 18 Jul 2018 19:11
URI: http://repository.unair.ac.id/id/eprint/73243
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