Sintesis Senyawa Baru N-benzoilfenil-urea dan uji aktivitasnya sebagai penekan susunan saraf pusat

Bambang Tri Purwanto (2011) Sintesis Senyawa Baru N-benzoilfenil-urea dan uji aktivitasnya sebagai penekan susunan saraf pusat. Majalah Farmasi Airlangga (Airlangga Journal of Pharmacy), 9 (1). ISSN 0852-1050

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Abstract

Synthesis the new compound N-benzoylphenilurea has been done. The Schotten Baumann method was used for the reaction between Niphenylurea and benzoyl chloride. The CNS depressant activitytest was done for the Nsbenzoylphenylura compound by Barbituric Sleeping Time (BST) method The compound yield was 86% , had a white crystal and gave one spot in Thin Layer Chromatography with two different eluent. The compound melting point was different from the N­phenylurea and showed greater. The structure identification from the new compound was analysed by JR, HNMR and MS, the result showed that the new compound was Nvbenzoyiphenylurea The CNS depressant activity The CNS depressant activity test from Nsbenzoylphenylurea had a greater activity if compare with the standard compound bromisoval

Item Type: Article
Uncontrolled Keywords: Nsbenzoylphenilurea; CNS depressant
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM/NIDN
Bambang Tri Purwantobambang-t-p@ff.unair.ac.id
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 06 Jan 2019 04:14
Last Modified: 24 Jun 2019 01:45
URI: http://repository.unair.ac.id/id/eprint/77668
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