PENGARUH VIRGIN COCONUT OIL (VCO)TERHADAP JUMLAH MAKROFAG PADA LUKA PASCAEKSTRAKSI GIGI TIKUS WISTAR

ANDRY SENTOSA, 021511133014 (2018) PENGARUH VIRGIN COCONUT OIL (VCO)TERHADAP JUMLAH MAKROFAG PADA LUKA PASCAEKSTRAKSI GIGI TIKUS WISTAR. Skripsi thesis, Fakultas Kedokteran Gigi.

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Abstract

Background: Macrophages are the initiator of the wound healing phase, a very important role in wound healing. Virgin Coconut Oil (VCO) is natural coconut oil, grown in Indonesia. VCO is useful as an anti-inflammatory, anti-oxidant and antibacterial. This study aimed at VCO on the number of macrophages after extraction of Wistar rat teeth. Materials and Methods: This type of research is true experimental only posttest control group design. 8 groups of Wistar rats were divided randomly. The treatment group was given VCO of 1.01 ml / 250 g per day (0.04 / 10 gr weight rats / day), for 7 days, 9 days, 11 days and 13 days. Extraction of rat teeth was carried out on the eighth day. Compile the number of macrophages: first, third, fifth and seventh day after extraction. Results: The number of macrophages on the first day after dental extraction 2 was higher in the intervention group than in the control group, but it did not showed a significant difference p = 0.607. The third day after tooth extraction showed a significant difference in the number of macrophages, with an average 3.5 macrophages (p = 0.046), the fifth days after tooth extraction and the seventh days after tooth extraction still showed a significant difference with a smaller mean value of 2.75 (p = 0.028 ) and 2.5 macrophages (p = 0.028). Conclusion: VCO was proven to increase the number of macrophages, with the most effective dose of 1.01 ml / 250 g BB rats per day (0.04 / 10 gr BB rats / day) for 9 days.

Item Type: Thesis (Skripsi)
Additional Information: KKA KK KG 159/18 Sen p
Uncontrolled Keywords: VCO, NUMBER OF MACROPHAGES, TOOTH EXTRACTION.
Subjects: R Medicine > RK Dentistry > RK1-715 Dentistry
Divisions: 02. Fakultas Kedokteran Gigi
Creators:
CreatorsNIM/NIDN
ANDRY SENTOSA, 021511133014UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorR. SOESANTO, drg., M.Kes., Sp.BM(K)UNSPECIFIED
ContributorACHMAS HARIJADI, Dr., drg., M.Kes.Sp.BM(K)UNSPECIFIED
Depositing User: Ani Sistarina
Date Deposited: 07 Jan 2019 07:42
Last Modified: 08 Jan 2019 04:16
URI: http://repository.unair.ac.id/id/eprint/77749
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