POTENSI ANTIOKSIDAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP JUMLAH SEL SPERMATOGENIK DAN SEL SERTOLI MENCIT JANTAN (Mus musculus) DENGAN PAPARAN SUHU PANAS

KRISTOFORUS ARNOLD KOSASIH, 061511133062 (2019) POTENSI ANTIOKSIDAN EKSTRAK KULIT BUAH NAGA MERAH (Hylocereus polyrhizus) TERHADAP JUMLAH SEL SPERMATOGENIK DAN SEL SERTOLI MENCIT JANTAN (Mus musculus) DENGAN PAPARAN SUHU PANAS. Skripsi thesis, Universitas Airlangga.

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Abstract

The aim of this research was to know whether red dragon fruit (Hylocereus polyrhizus) peel extract could protect spermatogenic and sertoli cell in mice (Mus musculus) exposured to heat temperature. Mice were exposed to a temperature of 40oC, 45 minutes daily, for 36 days. This study used twenty mice which were devided equally into 5 groups. K(-), the negative control group was not exposed to heat and only given 1% CMC-Na suspension. K(+), the positive control group was exposed to heat and given 1% CMC-Na suspension. P1, P2 and P3 were given red dragon fruit peel with doses of 250, 500, and 1000 mg/kg BW respectively 5 minutes after heat exposure. All of the treatment were given orally (0,5 ml). The observations showed significantly different (p<0,05) in all of variable. Result showed significant difference in spermatogenic and sertoli cells between K(-) and K(+) groups, K(+) and P2 group, and showed unsignificant difference between P2 and K(-) group in spermatogenic and sertoli cells. The result of this research showed that red dragon fruit peel extract could protect the spermatogenic and sertoli cells in male mice exposured by heat. The optimal dose to protect the spermatogenic and sertoli cells was 500 mg/kgBW.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH. 94-19 Kos p
Uncontrolled Keywords: Hylocereus polyrhizus, heat exposure, spermatogenic cells, sertoli cells, Mus musculus.
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan > Ilmu Kedokteran Hewan Dasar
Creators:
CreatorsEmail
KRISTOFORUS ARNOLD KOSASIH, 061511133062UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorSuzanita Utama, drh., M.Phil., Ph.D.UNSPECIFIED
ContributorRochmah Kurnijasanti, Dr., drh., M.Si.UNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 12 Apr 2019 09:54
Last Modified: 12 Apr 2019 09:54
URI: http://repository.unair.ac.id/id/eprint/81818
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